FB2025_01 , released February 20, 2025
Gene Group: DNA ENDONUCLEASES
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General Information
Name
DNA ENDONUCLEASES
Species
D. melanogaster
Symbol
EDNASE
FlyBase ID
FBgg0001465
Date last reviewed
2020-06-16
Number of members
32
Description
Description
Endodeoxyribonucleases catalyze the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
Notes on Group
Source Material
The DNA ENDONUCLEASES Gene Group has been compiled using the following publication(s): Bellendir et al., 2017, Barclay et al., 2014, Kanno et al., 2007, Seong et al., 2006, and Nugent et al., 1993 .
Key Gene Ontology (GO) terms
Molecular Function
DNA endonuclease activity
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
DEOXYRIBONUCLEASES
Component group(s)
CLASS II APURINIC OR APYRIMIDINIC ENDONUCLEASES
CROSSOVER JUNCTION DNA ENDONUCLEASES
DEOXYRIBONUCLEASES I
DEOXYRIBONUCLEASES II
FLAP ENDONUCLEASES
SINGLE-STRANDED DNA ENDONUCLEASES
UNCLASSIFIED DNA ENDONUCLEASES
Members (32)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
CLASS II APURINIC OR APYRIMIDINIC ENDONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG6171
(FlyBase, 2017-, Kanno et al., 2007)
RpLP0
Ribosomal protein LP0
RpP0, AP3, PO, LP0, Ape
(FlyBase, 2017-)
Rrp1
Recombination repair protein 1
APEX1
(FlyBase, 2017-, Nugent et al., 1993)
CROSSOVER JUNCTION DNA ENDONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gen
XPG-like endonuclease
mus324, DmGEN, BcDNA:GM10765
(Bellendir et al., 2017, FlyBase, 2017-)
mus81
mus81
EG:BACR7A4.16
(FlyBase, 2017-)
slx1
nuclease slx1
(FlyBase, 2017-)
DEOXYRIBONUCLEASES I
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Dcr-1
Dicer-1
Dicer, Dcr1
(FlyBase, 2017-)
Dcr-2
Dicer-2
Dcr2, Dicer, dmDcr-2, dcr
(FlyBase, 2017-)
DEOXYRIBONUCLEASES II
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
DNaseII
Deoxyribonuclease II
DNase1, dDNase II
(FlyBase, 2017-, Seong et al., 2006)
FLAP ENDONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Dna2
DNA replication helicase/nuclease 2
mus109, mus-109, mus(1)109
(FlyBase, 2017-)
Fen1
Flap endonuclease 1
EG:EG0003.3
(FlyBase, 2017-, Barclay et al., 2014)
Gen
XPG-like endonuclease
mus324, DmGEN, BcDNA:GM10765
(Bellendir et al., 2017, FlyBase, 2017-, Barclay et al., 2014)
mus81
mus81
EG:BACR7A4.16
(Bellendir et al., 2017, FlyBase, 2017-, Barclay et al., 2014)
mus201
mutagen-sensitive 201
mus(2)201, mus-201, XPG, ESTS:55A11T, DmXPG
(FlyBase, 2017-)
slx1
nuclease slx1
(FlyBase, 2017-)
tos
tosca
(FlyBase, 2017-)
SINGLE-STRANDED DNA ENDONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG3819
(FlyBase, 2017-)
CG6839
(FlyBase, 2017-)
CG12917
(FlyBase, 2017-)
CG14062
(FlyBase, 2017-)
CG14118
(FlyBase, 2017-)
CG14120
(FlyBase, 2017-)
CG33346
(FlyBase, 2017-)
mei-9
meiotic 9
mei9, mus110
(FlyBase, 2017-)
mre11
meiotic recombination 11
(FlyBase, 2017-)
Sid
Stress induced DNase
(FlyBase, 2017-)
Tengl1
Testis EndoG-Like 1
(FlyBase, 2017-)
Tengl2
Testis EndoG-Like 2
(FlyBase, 2017-)
Tengl3
Testis EndoG-Like 3
(FlyBase, 2017-)
Tengl4
Testis EndoG-Like 4
(FlyBase, 2017-)
UNCLASSIFIED DNA ENDONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG7139
BcDNA:LD21293
(FlyBase, 2017-)
CG8679
(FlyBase, 2017-)
CG42391
(FlyBase, 2017-)
Drep4
DNA fragmentation factor-related protein 4
dCAD, Rep4, CAD
(FlyBase, 2017-)
EndoG
Endonuclease G
(FlyBase, 2017-)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
EDNASE
ENDODEOXYRIBONUCLEASES
DNA ENDONUCLEASES
Secondary FlyBase ID(s)
References (7)