FB2026_02 , released June 18, 2026
Aberration: Dmel\Df(2R)ES1
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General Information
Symbol
Df(2R)ES1
Species
D. melanogaster
Name
FlyBase ID
FBab0001956
Feature type
chromosomal_deletion
Computed Breakpoints include

60E6;60F1-60F2

Features within 60E6--60F2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
ethyl methanesulfonate
(Gotwals and Fristrom, 1991, Cote et al., 1987)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Germeraad et al., 1992, Gotwals and Fristrom, 1991, Cote et al., 1987)
Breakpoints

[];60F1--2

(Cote et al., 1987)

60E6-60E8;60F1-60F2

(Gotwals and Fristrom, 1991)

60E5-60E6;60F1-60F2

(Germeraad et al., 1992)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Dll << bk1 << RpL19 << Tkr << bk2

Genetic mapping information
Comments

60F1-2 break at +54 kb.

Comments on Cytology

Ref: Cote et al., 1987, EMBO J. 6(9): 2793--2802

(Germeraad et al., 1992)

Left limit of break 1 from polytene analysis (FBrf0054179) Right limit of break 1 from polytene analysis (FBrf0056560) Left limit of break 2 from inclusion of Tkr (FBrf0046110) Right limit of break 2 from polytene analysis (FBrf0046110)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
gol
(Cote et al., 1987)
gsb
(Cote et al., 1987)
gsb-n
(Cote et al., 1987)
ifm(2)RS5
(Babu and Ramachandra, 2007)
lov
(Cote et al., 1987)
RpL19
(Hart et al., 1993)
zip
(Bayer et al., 2003, Young et al., 1993, Gotwals and Fristrom, 1991, Cote et al., 1987)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2R)ES1 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the suppressor maps to the tip of 2L rather than to the site of the deficiency. In addition, the 2L TAS array on the chromosome is missing (as assayed by in situ hybridization) and it has previously been shown (FBrf0137248, FBrf0158986) that partial or complete deficiency of the 2L TAS array on the homologue suppresses silencing of brown-red variants of P{3'WP-2,wvar}2Lt.

    (Mason et al., 2004)

    Df(2R)ES1/Df(2R)gsb embryos fail to complete dorsal closure.

    (Young et al., 1993)

    Second breakpoint not reported.

    (Cote et al., 1987)
    Synonyms and Secondary IDs (6)
    Reported As
    Symbol Synonym
    BL-3157
    (Edgar et al., 2005)
    Df(2R)ES1
    (Babu and Ramachandra, 2007)
    Df(2R)ESI
    (Crest et al., 2007)
    Df(2R)Es1
    (Presgraves, 2003)
    Df(2R)gsbES1
    (Germeraad et al., 1992)
    ES1
    (Harbecke and Lengyel, 1995)
    Name Synonyms
    Secondary FlyBase IDs
      References (23)