FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Ts(1Lt;4Lt)wm5
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General Information
Symbol
Ts(1Lt;4Lt)wm5
Species
D. melanogaster
Name
FlyBase ID
FBab0006556
Feature type
assortment_derived_aneuploid
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
T(1;4)wm5
Mutagen
segregation
Class of aberration (relative to wild type)
assortment_derived_aneuploid
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

A block of X heterochromatin is just distal to the w locus (from In(1)wm4h) such that the w locus is flanked proximally by 4th chromosome heterochromatin and distally by X heterochromatin. It is suggested that the block of X heterochromatin is responsible for the large size of Ts(1Lt;4Lt)wm5, three times the metaphase length of the 4th chromosome.

(Hawley et al., 1992)

Duplication 1.9 times the length of chromosome 4 at metaphase.

(Pipkin and Chakrabartty, 1975)
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
dor
(Hawley et al., 1992)
sc
(Hawley et al., 1992)
su(wa)
(Hawley et al., 1992)
w
(Hawley et al., 1992)
y
(Hawley et al., 1992)
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
ec
(Hawley et al., 1992)
N
(Hawley et al., 1992)
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Induces high frequency of 4th chromosome nondisjunction. Strong suppression of meiotic exchange across the distal third of the X chromosome.

    (Hawley et al., 1992)

    Ts(1Lt;4Lt)wm5 added to a normal male genome produces males with 20% normal viability that are weakly fertile; added to a diploid female genome, it produces a fertile hyperploid genome; and added to a triploid intersex genome, it is virtually lethal.

    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Dp(1;4)wm5
    (Irick, 1994, Hawley et al., 1993, Hawley et al., 1992)
    Ts(1Lt;4Lt)wm5
    Name Synonyms
    Secondary FlyBase IDs
    • FBab0023012
    References (4)