FB2026_02 , released June 18, 2026
Aberration: Dmel\Df(1)4b18
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General Information
Symbol
Df(1)4b18
Species
D. melanogaster
Name
FlyBase ID
FBab0022047
Feature type
chromosomal_deletion
Computed Breakpoints include

14B8;14C1

Features within 14B8--14C1
Sequence coordinates
X:16,363,428..16,363,994 [+] (Df(1)4b18:bk2)
(Stanewsky et al., 1993)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Stanewsky et al., 1993)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Cook et al., 1997, Rutherford, 1995, Stanewsky et al., 1993)
Breakpoints

14B8;14C1

(Cook et al., 1997, Rutherford, 1995, Stanewsky et al., 1993)
Causes alleles
nonA4b18
(Stanewsky et al., 1993)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << l(1)9e3-21 << l(1)XR49 << bk2 << nonA

Genetic mapping information
Comments
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0064715) Left limit of break 2 from inclusion of U2af50 (FBrf0064715) Right limit of break 2 from polytene analysis (FBrf0064715)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Larval mouthpart structures appear normal in Df(1)4b18 embryos when Dp(1;4)81j6e is also present.

    (Mahaffey et al., 2001)

    Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)4b18 weakly decreases transmission.

    (Cook et al., 1997)
    NOT in combination with other aberrations

    Hemizygous male embryos lack the base of the mouth hooks and dental sclerites. The lateral process is truncated near the H-piece, which is also disrupted. The few remaining cirri are misshapen and disorganised. The maxillary portion of the maxillary sense organ does not fuse with the antennal portion.

    (Mahaffey et al., 2001)

    Heterozygous adults show a weakly penetrant β lobe fusion phenotype in the central brain.

    (Boquet et al., 2000)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)
    Stocks (2)
    Notes on Origin
    Discoverer

    Stanewsky.

    (Stanewsky et al., 1993)
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    70kb deletion that breaks within the second exon of the nonA gene.

    (Stanewsky et al., 1993)
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Df(1)4b18
    (Haynes, 2017.5.2, Parker et al., 2011, Becalska and Gavis, 2010, Crest et al., 2007)
    Name Synonyms
    Secondary FlyBase IDs
      References (19)