FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)Trf-C6R31
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General Information
Symbol
Df(2L)Trf-C6R31
Species
D. melanogaster
Name
Df(2L)TBP-related factor-C6R31
FlyBase ID
FBab0022203
Feature type
chromosomal_deletion
Also Known As
Df(2L) Trf-C6R31
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{lacW}Trf1
(Crowley et al., 1993)
P{lacW}Trf2
(Crowley et al., 1993)
Mutagen
Delta2-3 transposase
(Crowley et al., 1993)
Class of aberration (relative to wild type)
chromosomal_deletion
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Bsg
(BDGP Project Members, 1994-1999)
l(2)k06327
(BDGP Project Members, 1994-1999)
Mcr
(Bätz et al., 2014, Crowley et al., 1993)
MED20
(Crowley et al., 1993)
Trf
(Crowley et al., 1993)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Heterozygosity for Df(2L)Trf-C6R31 results in 1.7% X chromosome nondisjunction and 1.9% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Homozygotes show embryonic lethality.

    (Crowley et al., 1993)
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2L)Trf-C6R31 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is assumed to be a false positive result (the suppressor may not be within the bounds of the deficient region) because the 2L TAS array on the chromosome is reduced (as assayed by in situ hybridization) and it has previously been shown (FBrf0137248, FBrf0158986) that partial or complete deficiency of the 2L TAS array on the homologue suppresses silencing of brown-red variants of P{3'WP-2,wvar}2Lt.

    (Mason et al., 2004)

    "FBti0003098 == P{lacW}Trf1" was stated as tentative. "FBti0003099 == P{lacW}Trf2" was stated as tentative.

    (Crowley et al., 1993)
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Df(2L) TRF-C6R31
    (Fiehler and Wolff, 2008)
    Df(2L) Trf-C6R31
    (Jordan et al., 2006)
    Df(2L)Trf-C6R31
    (Bätz et al., 2014, Clough et al., 2014, Tanaka and Nakamura, 2008)
    Name Synonyms
    Df(2L)TBP-related factor-C6R31
    Secondary FlyBase IDs
      References (14)