FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3L)ED224
Open Close
General Information
Symbol
Df(3L)ED224
Species
D. melanogaster
Name
FlyBase ID
FBab0035336
Feature type
chromosomal_deletion
Computed Breakpoints include

[75B1-75B1];[75C6-75C6];

Features within 75B1--75C6Features within 75B3--75C1 (Observed cytology)
Genomic Maps
Sequence coordinates
3L:17,969,203..17,969,203 (Df(3L)ED224:bk1)
(DrosDel Project, 2007.6.25)
3L:18,398,519..18,398,519 (Df(3L)ED224:bk2)
(DrosDel Project, 2007.6.25)
Member of large scale dataset(s)
Dfs_DrosDel_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.

(Ryder et al., 2007)
Nature of Aberration
Cytological Order
Progenitor
P{RS3r}CB-0578-3
(Ryder, 2003.6.17)
P{RS5r}5-HA-1089
(Ryder, 2003.6.17)
Mutagen
FLPase
(Ryder, 2003.6.17)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Ryder, 2003.6.17)
Breakpoints

75B1;75C6

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P{3'.RS5+3.3'}ED224
(Ryder, 2003.6.17)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Removes the 75B3-75C1 bands, including the most distal part of the intercalary heterochromatin region.

(Andreyenkova et al., 2009)

Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.

(Ryder and Roote, 2005.11.4)

Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{lacW}l(3)j11B2j11B2 and P{PZ}W05014 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}W05014 and P{lacW}l(3)j14E7j14E7

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
mRpS26
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
jaft
(Collins and Cohen, 2005)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (40)
Phenotypic Data
In combination with other aberrations

Df(3L)MM2/Df(3L)ED224 mutant early-mid third instar larvae display supernumerary ventral neuroblasts compared with wild-type.

(Tan et al., 2011)

Df(3L)X14/Df(3L)ED224 larvae do not show a significant increase in abdominal neuroblasts compared to wild-type.

(Tan et al., 2011)

Inferred to overlap with: Df(3L)MM2.

(Tan et al., 2011)
NOT in combination with other aberrations

In contrast to controls, no chromosomal breaks in the 75C1-2 region are found in chromosomes bearing the deficiency.

(Andreyenkova et al., 2009)

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (3)
References (19)