FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3L)MM2
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General Information
Symbol
Df(3L)MM2
Species
D. melanogaster
Name
FlyBase ID
FBab0047109
Feature type
chromosomal_deletion
Also Known As
MM2
Computed Breakpoints include
Features within 75C3--75C6 (Estimated cytology)
Genomic Maps
Sequence coordinates
3L:18,287,985..18,287,985 (Df(3L)MM2:bk1)
(Tan et al., 2011)
3L:18,398,597..18,398,597 (Df(3L)MM2:bk2)
(Tan et al., 2011)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
PBac{WH}f07860
(Tan et al., 2011)
P{XP}rprd11052
(Tan et al., 2011)
Mutagen
FLPase
(Tan et al., 2011)
Class of aberration (relative to wild type)
chromosomal_deletion
(Tan et al., 2011)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Tan et al., 2011)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

FLP-mediated recombination between the two progenitor insertions has resulted in the deletion of the genomic sequence between them.

(Tan et al., 2011)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (8)
Phenotypic Data
In combination with other aberrations

Df(3L)MM2/Df(3L)MM3 animals have a defect in the programmed cell death of vCrz neurons: 13 +/- 1.4 neurons are present at 7 hours after puparium formation (APF) (these neurons are no longer present in wild-type animals at this stage) and 4.5 +/- 3.5 neurons are present at 16 hours APF.

(Lee et al., 2013)

Df(3L)MM2/Df(3L)XR38 animals have a defect in the programmed cell death of vCrz neurons: 13.6 +/- 2.2 neurons are present at 7 hours after puparium formation (APF) (these neurons are no longer present in wild-type animals at this stage) and 12.6 +/- 2.5 neurons are present at 16 hours APF. 0.5 +/- 0.6 surviving EW3-sib cells are seen in these animals (these cells die during embryogenesis in wild type).

(Lee et al., 2013)

The normal programmed cell death of vCrz neurons is completely blocked in Df(3L)MM2/Df(3L)X25 animals (assayed at 7 hours and 16 hours after puparium formation). 10 +/- 1.3 surviving EW3-sib cells are seen in these animals (these cells die during embryogenesis in wild type).

(Lee et al., 2013)

The normal programmed cell death of vCrz neurons is completely blocked in Df(3L)MM2/Df(3L)grim-A6C animals (assayed at 7 hours and 16 hours after puparium formation).

(Lee et al., 2013)

The normal programmed cell death of vCrz neurons is completely blocked in Df(3L)MM2/Df(3L)grim-A6C animals (assayed at 7 hours and 16 hours after puparium formation). 9.5 +/- 1.8 surviving EW3-sib cells are seen in these animals (these cells die during embryogenesis in wild type).

(Lee et al., 2013)

Df(3L)MM2/Df(3L)ED224 mutant early-mid third instar larvae display supernumerary ventral neuroblasts compared with wild-type.

(Tan et al., 2011)

Ventral neuroblast-clusters of Df(3L)grim-A6C/Df(3L)MM2 mutant larvae display supernumerary cells compared with wild-type.

(Tan et al., 2011)

Inferred to overlap with: Df(3L)ED224.

(Tan et al., 2011)

Inferred to overlap with: Df(3L)ED225.

(Tan et al., 2011)

Inferred to overlap with: Df(3L)grim-A6C.

(Tan et al., 2011)

Ventral neuroblast-clusters of Df(3L)MM2/Df(3L)ED225 mutant larvae display supernumerary cells compared with wild-type. Df(3L)MM2/Df(3L)ED225 is semi-lethal. The flies that emerge live for only one or two days.

(Tan et al., 2011)
NOT in combination with other aberrations

Heterozygous animals have a defect in the programmed cell death of vCrz neurons: 6.2 +/- 3.3 neurons are present at 7 hours after puparium formation (APF) (these neurons are no longer present in wild-type animals at this stage) and 1.3 +/- 1.1 neurons are present at 16 hours APF.

(Lee et al., 2013)
Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Df(3L)MM2
(Harding and White, 2019)
MM2
(Sun et al., 2020, Tan et al., 2011)
ΔMM2
(Lee et al., 2013)
Name Synonyms
Secondary FlyBase IDs
    References (4)