FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)slam
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General Information
Symbol
Df(2L)slam
Species
D. melanogaster
Name
FlyBase ID
FBab0047595
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 26C3--26D1 (Estimated cytology)
Genomic Maps
Sequence coordinates
2L:6,363,074..6,363,074 (Df(2L)slam:bk1)
(Acharya et al., 2014)
2L:6,411,326..6,411,326 (Df(2L)slam:bk2)
(Acharya et al., 2014)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
PBac{WH}f00173
(Acharya et al., 2014)
P{XP}d03327
(Acharya et al., 2014)
Mutagen
FLPase
(Acharya et al., 2014)
Class of aberration (relative to wild type)
chromosomal_deletion
(Acharya et al., 2014)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Acharya et al., 2014)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

FLP-mediated recombination between the two progenitor insertions (PBac{WH}f00173 and P{XP}d03327) has resulted in the deletion of the genomic sequence between them, removing several genes including slam.

(Acharya et al., 2014)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
CG42369
(Acharya et al., 2014)
DIP-ε
(Acharya et al., 2014)
Nepl4
(Acharya et al., 2014)
Nepl5
(Acharya et al., 2014)
Nepl6
(Acharya et al., 2014)
slam
(Acharya et al., 2014)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (6)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Maternally and zygotically Df(2L)slam mutant embryos (coming from mothers bearing Df(2L)slam germ line clones) have significantly shorter cellularization furrow compared to wild-type controls.

(Yan et al., 2017)

Embryos lacking maternal and zygotic slam function (Df(2L)slam homozygotes derived from females containing homozygous Df(2L)slam germ-line clones and with all deleted genes except slam rescued using M{Nepl4.+tAa} and M{CH321-69B06}) show no cleavage furrow invagination.

Embryos lacking zygotic slam function (Df(2L)slam homozygotes with all deleted genes except slam rescued using M{Nepl4.+tAa} and M{CH321-69B06}) form an incomplete cleavage furrow.

In embryos lacking maternal slam function (derived from females containing homozygous Df(2L)slam germ-line clones and with all deleted genes except slam rescued using M{Nepl4.+tAa} and M{CH321-69B06}), the cleavage furrow extends almost to normal length, and some embryos even complete cellularisation.

(Acharya et al., 2014)
Stocks (0)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Df slam
(Acharya et al., 2014)
Df(2L)slam
(Schmidt et al., 2018, Yan et al., 2017)
Name Synonyms
Secondary FlyBase IDs
    References (3)