FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ace14
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General Information
Symbol
Dmel\Ace14
Species
D. melanogaster
Name
FlyBase ID
FBal0000195
Feature type
allele
Associated gene
Dmel\Ace
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Incardona and Rosenberry, 1996)
Mutagen
ethyl methanesulfonate
(Hilliker et al., 1981)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Ace14 is rescued by Ace+mFa

      (Incardona and Rosenberry, 1996)
      Partially rescued by

      Ace14 is partially rescued by AceTM.Tag:TM(HSV1-gC)

      (Incardona and Rosenberry, 1996)
      Comments

      Ace14/Df(3R)l26d flies rescued by Ace+mFa occasionally show a bang-sensitive phenotype; flies subjected to mechanical shock sometimes produce a burst of uncoordinated motor activity followed by paralysis, from which they recover in approximately 30 seconds. Hemizygotes carrying two copies of AceTM.T:Hsim\gC often die as pharate adults. Surviving adults are often bang-sensitive and die several days after eclosion. Adults are sometimes uncoordinated and have reduced locomotor activity and climbing scores. Grooming behaviour is also abnormal.

      (Incardona and Rosenberry, 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Hilliker, Clark.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ace14
      H89
      (Incardona and Rosenberry, 1996)
      l(3)H89
      (Hilliker et al., 1981)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)