FlyBase Allele Report: Dmel\Antp[2]

General Information

Symbol

Dmel\Antp²

Species

D. melanogaster

Name

FlyBase ID

FBal0000543

Feature type

allele

Associated gene

Dmel\Antp

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

X ray

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

Mutagen

X ray

(Abbott and Kaufman, 1986)

Progenitor genotype

Caused by aberration

Df(3R)Antp2

Cytology

Description

Breakpoint within the Antp transcription unit.

(Southworth and Kennison, 2002)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Deficient for a dorsal thoracic function and retain normal leg-specific function.

(Abbott and Kaufman, 1986)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Antp², ct^C145 has visible phenotype

(Johnston et al., 1998)

Antp², ct^L188 has visible phenotype

(Johnston et al., 1998)

Phenotype Manifest In

Other

Statement

Reference

Antp², ct^C145 has humeral bristle phenotype

(Johnston et al., 1998)

Antp², ct^C145 has pronotum phenotype

(Johnston et al., 1998)

Antp², ct^C145 has postpronotum phenotype

(Johnston et al., 1998)

Antp², ct^L188 has humeral bristle phenotype

(Johnston et al., 1998)

Antp², ct^L188 has pronotum phenotype

(Johnston et al., 1998)

Antp², ct^L188 has postpronotum phenotype

(Johnston et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

In heterozygous combination with ct^L188 or ct^C145, ectopic structures project (usually unilaterally) from the position of the anterior spiracle on the dorsal prothorax, and are associated with malformation of absence of the two macrochaetaes on the humeral callus. The phenotype is incompletely penetrant and not as severe as for Antp¹¹.

(Johnston et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

1941