The Malpighian tubules deformities characteristic for BicC5 homozygous mutant adults are partially rescued by expression of either MycJF01762 or MycJF01761 (leads to weaker rescue) under the combined control of Scer\GAL4c42 and Scer\GAL4tsh-c724 drivers: the incidence of cysts is significantly reduced in the terminal and in the proximal tubule, the tubular swelling and the irregular distribution of cell nuclei is also reduced compared to controls.
72% of embryos derived from BicC5/aretQB females hatch. 65% of embryos derived from BicC5/+ ; orbmel/+ females hatch. Of the non-hatching embryos, 39% are bicaudal and 52% have head defects. 30% of embryos derived from BicC5/+ ; orbF303/+ females hatch. Of the non-hatching embryos, 62% are bicaudal and 30% have head defects. 87% of embryos derived from BicC5/+ ; orbF343/+ females hatch.