FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\MycJF01762
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General Information
Symbol
Dmel\MycJF01762
Species
D. melanogaster
Name
FlyBase ID
FBal0219811
Feature type
allele
Associated gene
Dmel\Myc
Associated Insertion(s)
Carried in Construct
P{TRiP.JF01762}
Also Known As
UAS-dMycRNAi, UAS-dMyc RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009.1.15)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009.1.15)
Mutagen
in vitro construct
(Perkins et al., 2009.1.15)
Progenitor genotype
Carried in construct
P{TRiP.JF01762}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.1.15)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF01762
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4Cg.PA MycJF01762 animals reach pupation with a delay of 48h at their third instar transition; these animals are smaller throughout development and are pupal lethal.

      (Parisi et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      MycJF01762, Scer\GAL4ptc-559.1 is a suppressor | partially of hyperplasia phenotype of NUAS.icd, Scer\GAL4ptc-559.1

      (Djiane et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The Malpighian tubules deformities characteristic for BicC5 homozygous mutant adults are partially rescued by expression of MycJF01762 under the combined control of Scer\GAL4c42 and Scer\GAL4tsh-c724 drivers: the incidence of cysts is significantly reduced in the terminal and in the proximal tubule, the tubular swelling and the irregular distribution of cell nuclei is also reduced compared to controls.

      (Gamberi et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      MycJF01762 is rescued by Scer\GAL4Cg.PA/MycUAS.Tag:HA

      (Parisi et al., 2013)
      Comments

      Co-expression of MycScer\UAS.T:Ivir\HA1 rescues the small size and lethality of MycJF01762 Scer\GAL4Cg.PA animals.

      (Parisi et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      MycJF01762
      dmJF01762
      dmycJF01762
      (Chanu and Sarkar, 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (15)