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General Information
Symbol
Dmel\crn3
Species
D. melanogaster
Name
FlyBase ID
FBal0001843
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
crnRC63, RC63
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

3.6kb insertion within transcription unit.

2.5 kb insert at coordinate +66

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Hemizygotes display defects in CNS and PNS development. CNS has significantly fewer axons to make up the longitudinal connectives and the intersegmental and segmental nerves in embryos. The PNS has few or no chordotonal organs. Midgut constrictions do not appear, late embryos have a solid yolk plug.

Hemizygous embryos show contorsion and die.

crn3/Df(1)64c18 exhibits a similar phenotype to crn1 but more extreme phenotype, suggesting that it is hypomorphic. Lethal in female germ-line clones.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

crn3 is an enhancer of haltere sensillum phenotype of Ubx9.22

crn3 is an enhancer of haltere sensillum phenotype of Ubx195

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Rescued by P element carrying wild type genomic region.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

Lefevre.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)