W288term | Ubx-PA; W271term | Ubx-PC; W262term | Ubx-PD; W279term | Ubx-PE
Position of mutation on reference sequence inferred by FlyBase curator based on author statement. See Figure 2c of FBrf0046283. Nonsense codon only causes termination in transcripts which use this exon. These transcripts should terminate 7 amino acids before the start of the homeobox.
Polytene chromosomes normal.
UAG stop codon in mII. Inactivates Ubx isoforms Ia/b and IIa/b, but not IVa.
Single nucleotide change that introduces a nonsense codon in the exon at -53kb.
Amino acid replacement: ??term.
Nucleotide substitution: G?A.
Point mutation in the -50kb microexon, which generates a nonsense codon in the open reading frame of transcripts that use this microexon. Proteins encoded by these transcripts should terminate 7 amino acids before the start of the homeobox.
chordotonal organ & axon
Keilin's organ & abdominal segment 1
peripheral nervous system & parasegment 5
peripheral nervous system & parasegment 6