FlyBase Allele Report: Dmel\dpy[D]

General Information

Symbol

Dmel\dpy^D

Species

D. melanogaster

Name

Dominant

FlyBase ID

FBal0002902

Feature type

allele

Associated gene

Dmel\dpy

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(del Campo, 1963)

Progenitor genotype

Caused by aberration

T(2;3)dp^D

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage | dominant

(Kandasamy et al., 2021)

lethal | recessive

(del Campo, 1963)

visible | adult stage | dominant

(Kandasamy et al., 2021)

visible | dominant

(del Campo, 1963)

Phenotype Manifest In

adult thorax & adult epidermis

thorax

(del Campo, 1963)

wing

(Kandasamy et al., 2021, del Campo, 1963)

Detailed Description

Statement

Reference

dpy^D heterozygotes show a mild small, oblique wing phenotype.

(Kandasamy et al., 2021)

Heterozygotes exhibit a slight oblique wing effect and moderate vortex and comma effects on the thorax. Transheterozygotes with dp^lv1 are lethal. Transheterozygotes with dp^v or dp^v2 have strongly enhanced thorax effects. Transheterozygotes with dp^o have strongly truncated wings with possible enhancement of thorax effects.

(del Campo, 1963)

Oblique wing phenotype (o). Thoracic vortex phenotype (v). dp^D/+ has slightly oblique wing and moderate vortex and comma effects on thorax. dp^D/dp^ov1 has strong wing and thorax effects with reduced leg and body size. dp^D/dp^olv is lethal, and dp^D resembles dp^olv in several ways. dp^D/dp^v has strongly enhanced thorax effects, and dp^o/dp^D has reduced wings with possibly enhanced thoracic effect. RK2A.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

dpy^D has visible | adult stage phenotype, enhanceable by Yif1^doc-1/Yif1[+]

(Kandasamy et al., 2021)

dpy^D has decreased size | adult stage phenotype, enhanceable by Yif1^doc-1/Yif1[+]

(Kandasamy et al., 2021)

dpy^D has visible | adult stage phenotype, enhanceable by Sar1[+]/Sar1⁰⁵⁷¹²

(Kandasamy et al., 2021)

dpy^D has decreased size | adult stage phenotype, enhanceable by Sar1[+]/Sar1⁰⁵⁷¹²

(Kandasamy et al., 2021)

dpy^D has visible | adult stage phenotype, enhanceable by Sec13⁰¹⁰³¹/Sec13[+]

(Kandasamy et al., 2021)

dpy^D has decreased size | adult stage phenotype, enhanceable by Sec13⁰¹⁰³¹/Sec13[+]

(Kandasamy et al., 2021)

NOT Enhanced by

Statement

Reference

dpy^D has visible | adult stage phenotype, non-enhanceable by Sec23[+]/Sec23^j13C8

(Kandasamy et al., 2021)

dpy^D has decreased size | adult stage phenotype, non-enhanceable by Sec23[+]/Sec23^j13C8

(Kandasamy et al., 2021)

dpy^D has visible | adult stage phenotype, non-enhanceable by Sec23[+]/Sec23^9G

(Kandasamy et al., 2021)

dpy^D has decreased size | adult stage phenotype, non-enhanceable by Sec23[+]/Sec23^9G

(Kandasamy et al., 2021)

NOT suppressed by

Statement

Reference

dpy^D has visible | adult stage phenotype, non-suppressible by Sec23[+]/Sec23^j13C8

(Kandasamy et al., 2021)

dpy^D has decreased size | adult stage phenotype, non-suppressible by Sec23[+]/Sec23^j13C8

(Kandasamy et al., 2021)

dpy^D has visible | adult stage phenotype, non-suppressible by Sec23[+]/Sec23^9G

(Kandasamy et al., 2021)

dpy^D has decreased size | adult stage phenotype, non-suppressible by Sec23[+]/Sec23^9G

(Kandasamy et al., 2021)

Other

Statement

Reference

dpy[+]/dpy^D, jagn^G4067 has partially lethal - majority die phenotype

(Kandasamy et al., 2021)

Phenotype Manifest In

Enhanced by

Statement

Reference

dpy^D has wing phenotype, enhanceable by Yif1^doc-1/Yif1[+]

(Kandasamy et al., 2021)

dpy^D has wing phenotype, enhanceable by Sar1[+]/Sar1⁰⁵⁷¹²

(Kandasamy et al., 2021)

dpy^D has wing phenotype, enhanceable by Sec13⁰¹⁰³¹/Sec13[+]

(Kandasamy et al., 2021)

NOT Enhanced by

Statement

Reference

dpy^D has wing phenotype, non-enhanceable by Sec23[+]/Sec23^j13C8

(Kandasamy et al., 2021)

dpy^D has wing phenotype, non-enhanceable by Sec23[+]/Sec23^9G

(Kandasamy et al., 2021)

NOT suppressed by

Statement

Reference

dpy^D has wing phenotype, non-suppressible by Sec23[+]/Sec23^j13C8

(Kandasamy et al., 2021)

dpy^D has wing phenotype, non-suppressible by Sec23[+]/Sec23^9G

(Kandasamy et al., 2021)

NOT Enhancer of

Statement

Reference

dpy^D/dp[+] is a non-enhancer of eye phenotype of Dref^UAS.cSa

(Ida et al., 2009)

NOT Suppressor of

Statement

Reference

dpy^D/dp[+] is a non-suppressor of eye phenotype of Dref^UAS.cSa

(Ida et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

1638

T(2;3)dp^D, dpy^D/SM1

Kyoto

106423

dpy^D/SM1

Notes on Origin

Discoverer

E.B. Lewis, 1962.

E.B. Lewis.

(del Campo, 1963)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

dp^D

(Ida et al., 2009)

dpy^D

(Kandasamy et al., 2021)

olv^D

Name Synonyms

Dominant

Secondary FlyBase IDs

References (5)

Report Sections

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