FlyBase Allele Report: Dmel\elB[2]

General Information

Symbol

Dmel\elB²

Species

D. melanogaster

Name

FlyBase ID

FBal0003652

Feature type

allele

Associated gene

Dmel\elB

Associated Insertion(s)

Carried in Construct

Also Known As

el²

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Ashburner et al., 1999.10.12, Davis et al., 1997, Lindsley and Zimm, 1992)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2L)A400)

(Davis et al., 1997)

lethal (with Df(2L)el28)

(Davis et al., 1997)

lethal (with Df(2L)TE35B-1)

(Davis et al., 1997)

lethal (with Df(2L)TE35B-6)

(Davis et al., 1997)

lethal (with Df(2L)TE35B-7)

(Davis et al., 1997)

lethal (with Df(2L)TE35BC-8)

(Davis et al., 1997)

lethal (with In(2L)TE35B-13)

(Davis et al., 1997)

partially lethal

(Lindsley and Zimm, 1992)

visible

(Lindsley and Zimm, 1992)

Phenotype Manifest In

Detailed Description

Statement

Reference

Class i allele.

(Davis, 2003.5.6)

Weak allele. Lethal in double heterozygous combination with Df(2L)TE35B-1, Df(2L)TE35BC-8, In(2L)TE35B-13, Df(2L)el28, Df(2L)A400 and Df(2L)TE35B-7 (rare Df(2L)el28, Df(2L)A400 and Df(2L)TE35B-7 adult escapers are occasionally seen). Semi-lethal in double heterozygous combination Df(2L)TE35B-6.

(Davis et al., 1997)

Weak allele; class i Homozygotes exhibit < 0.5% viability.

(Ashburner, 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Tp(2;2)A446/+, elB² has partially lethal - majority die phenotype

(Davis et al., 1997)

Df(2L)n78l3/+, elB² has partially lethal - majority die phenotype

(Davis et al., 1997)

Df(2L)fn3/+, elB² has partially lethal - majority die phenotype

(Davis et al., 1997)

Phenotype Manifest In

Enhancer of

Statement

Reference

elB² is an enhancer of chaeta phenotype of sna^Sco

(Davis et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Strongly enhances "Sco" alleles, shows semi-lethality with "l(2)35Ba" alleles of noc.

(Davis, 2003.5.6)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Maroni.

(Lindsley and Zimm, 1992)

Comments

May be an allele of noc.

(Davis, 2003.5.6)

Partially complements: elA¹. Maps to the right of elA¹; 0.02% recombination (Maroni).

(Lindsley and Zimm, 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

el²

(Davis, 2003.5.6, Davis et al., 1997, Lindsley and Zimm, 1992, Gubb et al., 1988, Ashburner et al., 1983)

el^GM2

(Lindsley and Zimm, 1992, Ashburner et al., 1982)

elB²

Name Synonyms

Secondary FlyBase IDs

FBal0003614

References (8)

Report Sections

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