Open Close
General Information
Symbol
Dmel\f1
Species
D. melanogaster
Name
FlyBase ID
FBal0003944
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
f
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of a gypsy element within an intron of the characterised transcripts at nucleotide 15673 in the same orientation as the f gene.

Single gypsy insert in the second intron at a site identical to the gypsy insert of fX.

Insertion of gypsy 150bp upstream of that in fK, and in the same orientation as that in fK.

Insertion of gypsy element.

A member of the right hand group of alleles. Contains a gypsy insert in a 3.8 kb EcoRI restriction fragment (Parkhurst and Corces, 1985) and 3.2 kb from a particular SalI restriction site (McLachlan, 1986). Orientation of gypsy element opposite that of the gene.

Insertion components
gypsy{}f-1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

fA homozygotes and fA/f1 transheterozygotes exhibit a fork-bristle phenotype.

Compared to controls, homozygous mutants show a reduced response to an auditory stimulus mimicking flies' courtship song.

Larvae exhibit a weak bristle phenotype within the denticles of all rows.

The f1 phenotype is not suppressed in flies carrying su(Hw)wt or su(Hw)Δ656-705 in a su(Hw)7/su(Hw)V background, partly suppressed in flies carrying su(Hw)Δ706-736, su(Hw)Δ673-943, su(Hw)Δ853-880 or su(Hw)Δ881-944 in a su(Hw)7/su(Hw)V background, and strongly or completely suppressed in flies carrying su(Hw)Δ2-203.673-943, su(Hw)Δ738-780, su(Hw)Δ2-203 or su(Hw)Δ782-944 in a su(Hw)7/su(Hw)V background.

Mild f bristle phenotype. Bristle phenotype is under the control of a second site modifier.

Flies have forked bristles. Phenotype is unaffected by mod(mdg4)ul.

Phenotype is not affected by DoaHD or Doa6.

f53a13/f1 females have a very slight forked phenotype.

moderate - moderate with both macrochaetae and microchaetae clearly affected suppressed by su(f) suppressed by su(Hw)2

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

f1 has phenotype, enhanceable by E(f)1

Suppressed by
Statement
Reference

f1 has phenotype, suppressible by su(f)8

f1 has phenotype, suppressible by su(f)12

f1 has phenotype, suppressible by su(f)13

f1 has phenotype, suppressible by su(f)14

f1 has phenotype, suppressible by su(f)27

f1 has phenotype, suppressible by su(f)28

f1 has phenotype, suppressible by su(Hw)V/su(Hw)V

f1 has phenotype, suppressible by su(f)1

f1 has phenotype, suppressible by su(f)2

f1 has phenotype, suppressible | partially by su(Hw)2

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

f1 ; ckKT9 double mutants show a slight reduction in both size and sharpness of the denticles compared to either single mutant.

m1 f1 ckKT9 triple mutants show almost no elongation of the denticles.

Phenotype is suppressed by a number of su(f) alleles. Strength of suppression of the f1 phenotype: su(f)1 > su(f)4 > su(f)12 > su(f)8.

f1 su(f)4 males and females are f+ at 17-18oC. f1 su(f)4/f1 su(f)1 females are f+, like f1 su(f)1/f1 su(f)1, at all temperatures. f1 su(f)2/f1 su(f)1 females are f+ at 24-25oC. f1 su(f)2/f5 su(f)1 females show suppression of the f mutant phenotype similar to that seen in f1 su(f)1/f5 su(f)1 females at 24-25oC. At 20-30oC, the f1 su(f)2/f5 su(f)1 combination shows suppression of the f mutant phenotype but bristles are Minute-like.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (1)
Stocks (813)
Notes on Origin
Discoverer

Bridges, 19th Nov. 1912.

Comments
Comments

Synonymy presumed (in FBrf0066905).

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
References (38)