FB2026_02 , released June 18, 2026
Allele: Dmel\fw1
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General Information
Symbol
Dmel\fw1
Species
D. melanogaster
Name
FlyBase ID
FBal0004898
Feature type
allele
Associated gene
Dmel\fw
Associated Insertion(s)
412{}fw1
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Leshko-Lindsay and Corces, 1997)
Mutagen
spontaneous
(Leshko-Lindsay and Corces, 1997)
Progenitor genotype
Associated Insertion(s)
412{}fw1
Cytology
Description

Insertion of a 412 retrotransposon at nucleotide 880, within the first intron.

(Leshko-Lindsay and Corces, 1997)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Deep furrows or folds in the retina of adult compound eyes. Ommatidial pattern is severely disorganised, the ommatidia and interommatidial bristles show altered morphology. Defects in the development of the mechanosensory bristles including the macrochaetae (bristles shafts shortened, gnarled or bent and have altered polarity), microchaetae and bristles surrounding the eye. Shortened head and scutellum. 10% fw1/Df(1)KA10 female progeny have wing defects; wings are not expanded or appear stringy and have separation of the wing blades.

      (Leshko-Lindsay and Corces, 1997)

      fw68/fw1 females have a fw mutant phenotype.

      (Kaufman, 1969)

      Eyes with vertical fold and furrows. Head and scutellum shortened. Bristles gnarled and shortened, especially the postscutellars. Best classification character is short, blunt notopleurals. Phenotype can become nearly wild type on inbreeding (Lefevre). RK2.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      fw1/fw[+] is an enhancer of visible | dominant phenotype of sogEP7

      (Araujo et al., 2003)

      fw1/fw[+] is an enhancer of visible | dominant phenotype of sogEP11

      (Araujo et al., 2003)
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      fw1 has phenotype, non-suppressible by su(Hw)2

      (Lindsley and Grell, 1968)
      Enhancer of
      Statement
      Reference

      fw1/fw[+] is an enhancer of wing vein phenotype of sogEP7

      (Araujo et al., 2003)

      fw1/fw[+] is an enhancer of wing vein phenotype of sogEP11

      (Araujo et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      fw1 is rescued by fw+t12.7

      (Leshko-Lindsay and Corces, 1997)
      Comments

      Eye and bristle defects of homozygous adults are rescued by fw+t12.7.

      (Leshko-Lindsay and Corces, 1997)
      Images (1)
      Stocks (6)
      Notes on Origin
      Discoverer

      Duncan, Nov. 1914.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      References (13)