FlyBase Allele Report: Dmel\sesB[9Ed-1]

General Information

Symbol

Dmel\sesB^9Ed-1

Species

D. melanogaster

Name

FlyBase ID

FBal0007350

Feature type

allele

Associated gene

Dmel\sesB

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Janca et al., 1986)

Progenitor genotype

Cytology

Description

Nucleotide substitution: G to A. Amino acid replacement: A144T.

(Zhang et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

X:10,782,091..10,782,091 [-]

Nucleotide change:

G10782091A

Reported nucleotide change:

G?A

Amino acid change:

Reported amino acid change:

A144T

(Zhang et al., 1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of mitochondrial metabolism disease

CEA

(Gokhale et al., 2019)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | female | recessive

(Zhang et al., 1999)

lethal | recessive

(Janca et al., 1986, Nash and Janca, 1983)

partially lethal - majority die (with sesB^org)

(Rikhy et al., 2003)

Phenotype Manifest In

Detailed Description

Statement

Reference

2% of the expected number of sesB^9Ed-1/sesB^org flies survive to adulthood.

(Rikhy et al., 2003)

Hemizygous female lethal.

(Zhang et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sesB^9Ed-6

(Janca et al., 1986)

sesB^9Ed-5

(Janca et al., 1986)

sesB^9Ed-4

(Janca et al., 1986)

sesB^9Ed-3

(Janca et al., 1986)

sesB^9Ed-2

(Janca et al., 1986)

sesB³

(Janca et al., 1986)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

4687

107837

Notes on Origin

Discoverer

Separable from: a separable X-linked lethal mutation.

(Zhang et al., 1999)

Comments

Shows some escapers over Df(1)v64f.

(Janca et al., 1986)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

A17

(Nash and Janca, 1983)

l(1)9Ed¹

l(1)A17

(Janca et al., 1986)

sesB^9Ed-1

(Gokhale et al., 2019)

sesB^9Ed1

(Rikhy et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close