FlyBase Allele Report: Dmel\sesB[9Ed-6]

General Information

Symbol

Dmel\sesB^9Ed-6

Species

D. melanogaster

Name

FlyBase ID

FBal0007355

Feature type

allele

Associated gene

Dmel\sesB

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Perrimon et al., 1984)

Progenitor genotype

Caused by aberration

In(1)sesB^9Ed-6

Cytology

Description

Amino acid replacement: ?112term.

(Zhang et al., 1999)

Nucleotide substitution: G?A.

(Zhang et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

X:10,782,262..10,782,262 [-]

Nucleotide change:

G10782262A

Reported nucleotide change:

G?A

Amino acid change:

Reported amino acid change:

?112term

(Zhang et al., 1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | female | recessive

(Zhang et al., 1999)

lethal | male

(Zhang et al., 1999)

lethal | maternal effect

(Perrimon et al., 1984)

lethal - all die before end of larval stage | recessive

(Perrimon et al., 1989)

partially lethal - majority die (with sesB^org)

(Rikhy et al., 2003)

some die during larval stage | recessive

(Perrimon et al., 1989)

Phenotype Manifest In

egg chamber | germline clone | maternal effect

(Perrimon et al., 1984)

ovariole | germline clone

(Perrimon et al., 1989)

Detailed Description

Statement

Reference

1.2% of the expected number of sesB^9Ed-6/sesB^org flies survive to adulthood.

(Rikhy et al., 2003)

Hemizygous male and female lethal.

(Zhang et al., 1999)

Homozygous sesB^9Ed-6 germline have abnormal egg chambers.

(Perrimon et al., 1984)

L1/L2 larval lethal abnormal oogenesis

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sesB^9Ed-5

(Janca et al., 1986)

sesB^9Ed-4

(Janca et al., 1986)

sesB^9Ed-3

(Janca et al., 1986)

sesB^9Ed-2

(Janca et al., 1986)

sesB^9Ed-1

(Janca et al., 1986)

sesB³

(Janca et al., 1986)

Rescued by

sesB^9Ed-6 is rescued by sesB^+t10.3

(Zhang et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Lefevre.

(Janca et al., 1986)

Comments

Maternal germline clonal analysis demonstrates abnormal oogenesis, dumpless phenotype.

(Perrimon et al., 1989)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

DC701

(Perrimon et al., 1989)

l(1)9Ed⁶

l(1)DC701

(Zhang et al., 1998)

l(1)EM31

(Janca et al., 1986)

sesB^9Ed-6

sesB^9Ed6

(Rikhy et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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