FlyBase Allele Report: Dmel\sesB[+t10.3]

General Information

Symbol

Dmel\sesB^+t10.3

Species

D. melanogaster

Name

FlyBase ID

FBal0101159

Feature type

allele

Associated gene

Dmel\sesB

Associated Insertion(s)

Carried in Construct

P{Ant2⁺sesB⁺10.3}

Key Links

Genomic Maps

JBrowse

Transgenic product class

genomic_DNA

(Zhang et al., 1999)

wild_type

(Zhang et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Zhang et al., 1999)

wild_type

(Zhang et al., 1999)

Mutagen

in vitro construct

(Zhang et al., 1999)

Progenitor genotype

Carried in construct

P{Ant2⁺sesB⁺10.3}

Cytology

Description

10.3kb genomic fragment containing sesB and Ant2.

(Zhang et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

sesB

Encoded product / tool

sesB

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

rescue_region

X:10,777,573..10,787,985 [-]

Linked to:

HindIII-EcoRI restriction fragment

Comment:

Rescues the male lethality of lethal alleles of sesB and the stress-sensitive and hypoactive phenotypes of sesB¹ and sesB^9Ed-4.

(Zhang et al., 1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Zhang et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

sesB^+t10.3 is a non-suppressor of phenotype of Hmr¹

(Zhang et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

The hybrid rescue by Hmr¹ of the male progeny of D.melanogaster females crossed to D.mauritiana males is not suppressed by P{Ant2⁺sesB⁺10.3}. The hybrid rescue by In(1)AB of the male progeny of D.melanogaster females crossed to D.mauritiana, D.sechellia or D.simulans males is not suppressed by P{Ant2⁺sesB⁺10.3}.

(Zhang et al., 1999)

The hybrid rescue by Hmr¹ of the male progeny of D.melanogaster females crossed to D.mauritiana males is not suppressed by P{Ant2⁺sesB⁺10.3}. The hybrid rescue by Hmr² of the male progeny of D.melanogaster females crossed to D.mauritiana, D.sechellia or D.simulans males is not suppressed by P{Ant2⁺sesB⁺10.3}.