FlyBase Allele Report: Dmel\ex[01270]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\ex⁰¹²⁷⁰

General Information

Symbol

Dmel\ex⁰¹²⁷⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0007965

Feature type

allele

Associated gene

Associated Insertion(s)

P{PZ}ex⁰¹²⁷⁰

Carried in Construct

Also Known As

l(2)01270

Key Links

Genomic Maps

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}ex⁰¹²⁷⁰

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

reporter enzyme

Tagged with

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:431,860..431,860 [+]

(Abrell et al., 2000, Blaumueller and Mlodzik, 2000, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity | somatic clone

(Blaumueller and Mlodzik, 2000)

lethal | recessive

(Spradling et al., 1999)

partially lethal - majority die

visible | somatic clone

(Blaumueller and Mlodzik, 2000)

Phenotype Manifest In

eye | somatic clone

(Blaumueller and Mlodzik, 2000)

ommatidium | somatic clone

(Blaumueller and Mlodzik, 2000)

Detailed Description

Statement

Reference

Somatic clones in the eye exhibit weak patterning defects including chirality flips.

(Blaumueller and Mlodzik, 2000)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

ex⁰¹²⁷⁰ is an enhancer of visible | dominant phenotype of Kr^If-1

(Abrell et al., 2000)

Suppressor of

Statement

Reference

ex⁰¹²⁷⁰/ex[+] is a suppressor of visible phenotype of CycE^JP

(Brumby et al., 2004)

Phenotype Manifest In

Enhancer of

Statement

Reference

ex⁰¹²⁷⁰ is an enhancer of eye phenotype of Kr^If-1

(Abrell et al., 2000)

ex⁰¹²⁷⁰ is an enhancer of ommatidium phenotype of Kr^If-1

(Abrell et al., 2000)

Suppressor of

Statement

Reference

ex⁰¹²⁷⁰/ex[+] is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

ex⁰²²⁷⁸

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

A. Spradling.

Comments

Comments

Complements: lwr^01519a. Complements: lwr⁰²⁸⁵⁸. Complements: dock⁰⁴⁷²³. Complements: ds⁰⁵¹⁴². Complements: Gsc⁰⁵³⁴¹. Complements: lwr⁰⁵⁴⁸⁶. Complements: α-Adaptin⁰⁶⁶⁹⁴. Complements: S⁰⁷⁰⁵⁶. Complements: kis⁰⁷⁸¹². Complements: l(2)k06506^k06506. Complements: l(2)k07005^k07005. Complements: l(2)k07308^k07308. Complements: l(2)k07005^k08218. Complements: l(2)k08915^k08915. Complements: kis^k11324. Complements: Nle^k13714. Complements: ebi^k16213. Complements: RpI135^k16513.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ex⁰¹²⁷⁰

l(2)01270

(Blaumueller and Mlodzik, 2000, Spradling et al., 1999)

l(2)01270⁰¹²⁷⁰

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections