FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ex02278
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General Information
Symbol
Dmel\ex02278
Species
D. melanogaster
Name
FlyBase ID
FBal0043372
Feature type
allele
Associated gene
Dmel\ex
Associated Insertion(s)
P{PZ}ex02278
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}ex02278
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes develop normally to the third larval instar. This instar is prolonged up to 8 days. Between days 4 and 8 approximately 90% of the homozygotes pupariate but die before metamorphosing. Imaginal discs of these animals show hyperplastic overgrowth.

      (Harvie et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      ex02278 is an enhancer of visible | dominant phenotype of KrIf-1

      (Abrell et al., 2000)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      ex02278 is an enhancer of eye phenotype of KrIf-1

      (Abrell et al., 2000)

      ex02278 is an enhancer of ommatidium phenotype of KrIf-1

      (Abrell et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: lwr02858. Complements: ds05142. Complements: Gsc05341. Complements: α-Adaptin06694. Complements: ebik16213. Complements: RpI135k16513.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ex02278
      l(2)0127002278
      l(2)02278
      (Abrell et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)