FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fand05488
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General Information
Symbol
Dmel\fand05488
Species
D. melanogaster
Name
FlyBase ID
FBal0008091
Feature type
allele
Associated gene
Dmel\fand
Associated Insertion(s)
P{PZ}Cables105488
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}Cables105488
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant larvae do not have defects in the establishment or maintenance of dendritic tiling in class IV dendrite arborisation (da) neurons.

      (Parrish et al., 2007)

      Longitudinal glial cells of the central nervous system remain in segmental clusters separated by gaps in homozygous embryos, and remain in a more lateral position than in wild-type. Pioneer neurons (aCC, pCC, vMP2, MP1 and dMP2) develop at abnormal positions and project their axons abnormally; the MP neurons project their axons peripherally instead of longitudinally, and the pCC and aCC neurons project their axons straight laterally instead of longitudinally.

      (Lekven et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      fandH124

      (Sauerwald et al., 2017)

      fandP218

      (Sauerwald et al., 2017)

      fandfas-2

      (Lekven et al., 1998)
      Comments

      The lethal fand05488 allele fails to complement both fandP218 and fandH124 alleles.

      (Sauerwald et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Precise excision of the P{PZ} element reverts the mutant phenotype to wild-type, indicating that the P{PZ} element is responsible for the mutant phenotype.

      (Lekven et al., 1998)

      Not allelic to shot.

      (Gregory and Brown, 1998)

      Complements: l(2)0057200572. Complements: l(2)0310503105. Complements: mam03505. Complements: mam03751. Complements: mam04215. Complements: l(2)k08708k08708. Complements: l(2)k10814k10814.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      P1411
      (Lekven et al., 1998)
      fand05488
      fas05488
      (Parrish et al., 2007)
      l(2)05488
      (Spradling et al., 1999)
      l(2)0548805488
      l(2)5488
      (Gregory and Brown, 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)