FlyBase Allele Report: Dmel\eff[s1782]

General Information

Symbol

Dmel\eff^s1782

Species

D. melanogaster

Name

FlyBase ID

FBal0011137

Feature type

allele

Associated gene

Dmel\eff

Associated Insertion(s)

P{lacW}eff^s1782

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{lacW}eff^s1782

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:14,740,700..14,740,700 [+]

(Neufeld et al., 1998, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with eff^mer1)

(Fauvarque et al., 2001)

lethal (with eff^mer4)

(Fauvarque et al., 2001)

lethal | recessive

(BDGP Project Members, 1994-1999)

Phenotype Manifest In

female germline stem cell (with eff⁸)

(Chen et al., 2009)

female germline stem cell | germline clone

(Chen et al., 2009)

Detailed Description

Statement

Reference

The average number of germline stem cells per germarium is reduced in 14 day old eff⁸/eff^s1782 females compared to controls.

Homozygous eff^s1782 germline stem cell clones are lost more quickly from ovaries compared to control clones.

(Chen et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

eff^s1782 has abnormal neuroanatomy phenotype, enhanceable by Ube3a^Δ15-8

(Lu et al., 2009)

Enhancer of

Statement

Reference

eff^s1782 is an enhancer of abnormal neuroanatomy phenotype of Ube3a^Δ15-8

(Lu et al., 2009)

Suppressor of

Statement

Reference

eff^s1782/eff[+] is a suppressor of visible phenotype of Scer\GAL4^GMR.PF, neur^UAS.cLa

(Lai et al., 2001)

eff^s1782/eff[+] is a suppressor | partially of visible phenotype of Scer\GAL4^GMR.PF, neur^RING.UAS

(Lai et al., 2001)

NOT Suppressor of

Statement

Reference

eff^s1782/eff[+] is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, neur^αRING.UAS

(Lai et al., 2001)

Phenotype Manifest In

Enhanced by

Statement

Reference

eff^s1782 has larval dorsal multidendritic neuron ddaC phenotype, enhanceable by Ube3a^Δ15-8

(Lu et al., 2009)

Enhancer of

Statement

Reference

eff^s1782 is an enhancer of larval dorsal multidendritic neuron ddaC phenotype of Ube3a^Δ15-8

(Lu et al., 2009)

Suppressor of

Statement

Reference

eff^s1782/eff[+] is a suppressor of interommatidial bristle | increased number phenotype of Scer\GAL4^GMR.PF, neur^UAS.cLa

(Lai et al., 2001)

eff^s1782/eff[+] is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PF, neur^RING.UAS

(Lai et al., 2001)

NOT Suppressor of

Statement

Reference

eff^s1782/eff[+] is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, neur^αRING.UAS

(Lai et al., 2001)

eff^s1782/eff[+] is a non-suppressor of ommatidium phenotype of Scer\GAL4^GMR.PF, neur^αRING.UAS

(Lai et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Third-instar larva transheterozygous for As^Δ15-8 and eff^s1782 exhibit a severe reduction in the number of terminal dendritic branches of ddaC neurons compared to the single mutant heterozygotes.

(Lu et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

eff⁰¹⁴⁶²

(BDGP Project Members, 1994-1999)

Fails to complement

eff^mer4

(Fauvarque et al., 2001)

eff^mer1

(Fauvarque et al., 2001)

eff^unspecified

(Neufeld et al., 1998)

eff^j2C8

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

12140

w¹¹¹⁸; P{lacW}eff^s1782/TM3, Sb¹

Kyoto

111415

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}82B P{lacW}eff^s1782/TM6B, P{Car20y}TPN1, Tb¹

Notes on Origin

Discoverer

M. Scott.

Comments

Complements: btsz¹⁰⁴¹⁸.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

UbcD1^eff-s1782

(Fauvarque et al., 2001)

UbcD1^s1782

(Pan et al., 2017)

eff^S1782

(Ohlmeyer and Schupbach, 2003)

eff^s1782

(Chen et al., 2009, Lu et al., 2009)

l(3)1782

(Neufeld et al., 1998)

l(3)s1782^s1782

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

Open Close