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General Information
Symbol
Dmel\Ube3aΔ15-8
Species
D. melanogaster
Name
FlyBase ID
FBal0241530
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of P{EP}AsEP3214 leaves a 1.1kb DNA fragment from P{EP}AsEP3214 in As.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous AsΔ15-8 and transheterozygous AsΔ15-8/AsΔ3-8 third instar mutant larval ddaC neurons exhibit a significantly reduced number of dendritic terminal branches, although the overall branching patterns of ddaC neurons in the A3 segment, especially the primary and secondary branches, remain the same as in wild-type larvae.

Terminal dendritic branches of ddaC neurons in homozygous AsΔ15-8 and AsΔ15-8/AsΔ3-8 transheterozygous mutants are much shorter than in wild-type, with patches of the target field devoid of dendrites.

AsΔ15-8 mutant ddaC neurons (in an otherwise wild-type larva) exhibit defective dendritic growth (with fewer terminal dendritic branches) and branching.

The number of dendritic branches is decreased in ddaE and ddaF neurons that are homozygous for AsΔ15-8.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Enhancer of
Statement
Reference
Phenotype Manifest In
Enhanced by
Enhancer of
Additional Comments
Genetic Interactions
Statement
Reference

Third-instar larva transheterozygous for AsΔ15-8 and effmer4 exhibit a severe reduction in the number of terminal dendritic branches of ddaC neurons compared to the single mutant heterozygotes.

Third-instar larva transheterozygous for AsΔ15-8 and effs1782 exhibit a severe reduction in the number of terminal dendritic branches of ddaC neurons compared to the single mutant heterozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
AsΔ15-8
Ube3aΔ15-8
dUBE3AΔ15-8
Name Synonyms
Secondary FlyBase IDs
    References (1)