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General Information
Symbol
Dmel\Ube3aGD450
Species
D. melanogaster
Name
FlyBase ID
FBal0198772
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing Ube3aGD450 under the control of Scer\GAL4GMR.PU leads to a subtle rough eye phenotype.

Expression of Ube3aGD450 driven by Scer\GAL4elav.PU or Scer\GAL4RapGAP1-OK6 (but not Scer\GAL4C57) leads to a significant increase in total boutons (and satellite boutons) at the neuromuscular junction, compared to wild type third instar larvae.

Adults expressing Ube3aGD450 under the control of either Scer\GAL4elav.PU, Scer\GAL4Tab2-201Y or Scer\GAL4ey-OK107 show learning defects (significantly reduced performance in a aversive phototaxis suppression assay compared to controls).

Adults expressing Ube3aGD450 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Expression of AsGD450 in ddaC neurons under the control of Scer\GAL4477 in a AsΔ15-8 heterozygous background results in fewer terminal dendritic branches.

Expression of AsGD450 in ddaE and ddaF neurons under the control of Scer\GAL4221 decreases the number of dendritic branches.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
AsGD450
Ube3aGD450
Name Synonyms
Secondary FlyBase IDs
    References (12)