FlyBase Allele Report: Dmel\mor[6]

General Information

Symbol

Dmel\mor⁶

Species

D. melanogaster

Name

FlyBase ID

FBal0012416

Feature type

allele

Associated gene

Dmel\mor

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

gamma ray

Nature of the Allele

Allele class

loss of function allele

(Stevaux, 2002.3.12)

Mutagen

gamma ray

(Kennison and Tamkun, 1988)

Progenitor genotype

Cytology

Description

541bp deletion (nucleotides 2431 to 2970) and insertion of 233bp of DNA. This removes the leucine zipper and the carboxyl proline- and glutamine-rich sequences.

(Crosby et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Kennison and Tamkun, 1988)

visible | dominant

(Curtis et al., 2011)

Phenotype Manifest In

wing vein | ectopic

(Curtis et al., 2011)

Detailed Description

Statement

Reference

Heterozygotes often have ectopic wing vein material near the posterior crossvein.

(Curtis et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

mor⁶ has visible | dominant phenotype, enhanceable by Su(var)3-3[+]/Su(var)3-3^ΔN

(Curtis et al., 2011)

Enhancer of

Statement

Reference

mor⁶/mor[+] is an enhancer of visible | dominant phenotype of Snr1^E1

(Curtis et al., 2011)

Other

Statement

Reference

γTub23C^Pl-2, mor⁶ has visible | dominant phenotype

(Vázquez et al., 2008)

Phenotype Manifest In

Enhanced by

Statement

Reference

mor⁶ has wing vein | ectopic phenotype, enhanceable by Su(var)3-3[+]/Su(var)3-3^ΔN

(Curtis et al., 2011)

Enhancer of

Statement

Reference

mor⁶/mor[+] is an enhancer of wing vein | ectopic phenotype of Snr1^E1

(Curtis et al., 2011)

Suppressor of

Statement

Reference

mor⁶ is a suppressor of phenotype of Pc⁴

(Kennison and Tamkun, 1988)

Other

Statement

Reference

γTub23C^Pl-2, mor⁶ has wing phenotype

(Vázquez et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

61% of Su(var)3-3^ΔN mor⁶ double heterozygotes have ectopic wing vein material.

(Curtis et al., 2011)

γTub23C^Pl-2 results in a held-out wing phenotype in double heterozygous combination with mor⁶ (19% penetrance).

(Vázquez et al., 2008)

Suppresses the extra sex comb phenotype of Pc⁴, Ts(YLt;2Lt)L124. Causes between 50% and 100% suppression of the Pc⁴/+ extra sex combs phenotype.

(Kennison and Tamkun, 1988)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

mor⁶ is rescued by mor^+t11.8

(Stevaux, 2002.3.12)

mor⁶/mor¹ is rescued by mor^+t11.8

(Crosby et al., 1999)

mor²/mor⁶ is rescued by mor^+t11.8

(Crosby et al., 1999)

mor⁵/mor⁶ is rescued by mor^+t11.8

(Crosby et al., 1999)

mor⁶/Df(3R)mor-7 is rescued by mor^+t11.8

(Crosby et al., 1999)

mor⁶/mor⁹ is rescued by mor^+t11.8

(Crosby et al., 1999)

mor⁶/mor¹⁰ is rescued by mor^+t11.8

(Crosby et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Complements Hel89B^89B.

(Crosby et al., 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Mor⁶

(Stevaux, 2002.3.12)

mor⁶

(Curtis et al., 2011, Di Stefano et al., 2011, Vázquez et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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