FlyBase Allele Report: Dmel\mys[olfC-x10]

General Information

Symbol

Dmel\mys^olfC-x10

Species

D. melanogaster

Name

FlyBase ID

FBal0013248

Feature type

allele

Associated gene

Dmel\mys

Associated Insertion(s)

Carried in Construct

Also Known As

olfC^X10

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Beumer et al., 2002)

abnormal smell perception

(Ayyub and Paranjape, 2002)

abnormal smell perception (with mys^olfC-x3)

(Ayyub et al., 2000)

abnormal smell perception (with mys^olfC-x5)

(Ayyub et al., 2000)

abnormal smell perception (with mys^olfC-x17)

(Ayyub et al., 2000)

abnormal smell perception | recessive

(Ayyub et al., 2000, Ayyub et al., 1990)

Phenotype Manifest In

neuromuscular junction

(Beumer et al., 2002)

Detailed Description

Statement

Reference

In the odour-induced jump test, homozygous mutants of mys^olfC-x10 are defective in response to ethyl acetate and iso-amyl acetate but not benzaldehyde, when compared to controls.

(Ayyub and Paranjape, 2002)

Mutant synapses at the larval neuromuscular junction show overgrowth.

(Beumer et al., 2002)

Mutants exhibit reduced olfactory responses to isoamyl acetate and ethyl acetate, whether homozygous or in combination with mys^olfC-x3, mys^olfC-x5 or mys^olfC-x17.

(Ayyub et al., 2000)

Homozygous adults show a reduced attraction to both ethyl acetate and iso-amyl acetate compared to wild-type in a slow chemotaxis assay. mys^olfC-x10/mys^olfC-x5, mys^olfC-x10/mys^olfC-x14 and mys^olfC-x10/mys^olfC-x17 flies are defective in their responses to both ethyl acetate and iso-amyl acetate.

(Ayyub et al., 1990)

reduced attraction to both ethyl and iso-amyl acetate

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

if^B2, mys^olfC-x10 has abnormal smell perception phenotype

(Ayyub et al., 2000)

if^k27e, mys^olfC-x10 has abnormal smell perception phenotype

(Ayyub et al., 2000)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

In the odour-induced jump test, mutants the transheterozygous combination of mys^olfC-x10 with sws^olfE-x26 show normal response to iso-amyl acetate, ethyl acetate and benzaldehyde compared to controls.

(Ayyub and Paranjape, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

mys^{olfC-A459.1F1}

(Ayyub et al., 2000)

mys¹⁰

(Ayyub et al., 2000)

mys⁸

(Ayyub et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Rodrigues.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

mys^olfC-x10

olfC^X10

(Ayyub and Paranjape, 2002, Beumer et al., 2002, Ayyub et al., 2000)

olfC^x10

(Ayyub et al., 1990)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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