Adult ifB2 homozygous mutant intestinal stem cell clones have similar maintenance 7 days and 14 days after clone induction compared to control clones.
Fewer haemocytes are observed migrating into the tail region in ifB2 mutant embryos. There is no decrease in migration to the dorsal vessel or ventral nerve cord in these animals.
ifB2 mutant embryos develop a mild muscle detachment phenotype in several segments.
When tested in the odour-induced jump-test, double heterozygotes of swsolfE-x26 and ifB2 exhibit a reduced response to benzaldehyde, but not to iso-amyl acetate or ethyl acetate, compared to controls
Stage 14 oocytes carrying ifB2 somatic clones are much more rounded than wild-type.
Embryos exhibit normal epidermis and resultant secreted cuticle, defects lie in internal tissues. Somatic muscle detach and round up. Gut morphogenesis is defective: anterior midgut does not become a slender tube and only two fat gastric caecae are formed. The ventral nerve cord does not fully condense.
Homozygous embryos have an increased rate of axon errors in the central and peripheral nervous systems compared to wild-type.
Small clones (fewer than 150 cells) in the wing are often wild type or have a weak phenotype, even if on the ventral surface. mewH7 ifB2 double mutant small clones display a morphological phenotype.
Mitotic clones in the eye have normal morphology.
Clones in the eye do not exhibit photoreceptor disorganisation.
Extreme defects in somatic muscle attachment sites and morphogenesis of the midgut in the embryo. Muscles pull away from attachment sites at the onset of contractions. Ventral nerve cord fails to shorten completely. There is no dorsal herniation defect. Clonal analysis demonstrated that if function is only required in the cells of the ventral wing surface.