pll7/pll2 larvae show show mistargeting of the R2-R5 photoreceptor axons in the developing visual system; thickened bundles of axons along the entire length of the lamina are observed to penetrate into the medulla, while the lamina is not smooth and is somewhat irregular.
Level of Drs induction of bacterially challenged pll2/pll21 and pll2/pll10 mutants is lower than in wild type. Pattern of response of CecA1 and CecA2 parallels that of Drs. Dpt and Dro remain fully inducible and pattern of expression of AttA and Def in intermediate. Infection of pll2/pll21 mutants with A.fumigatus causes 4% survival 3 days postinfection, infection with E.coli causes 87% survival 3 days postinfection.