FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sd2
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General Information
Symbol
Dmel\sd2
Species
D. melanogaster
Name
FlyBase ID
FBal0015348
Feature type
allele
Associated gene
Dmel\sd
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Morcillo et al., 1996)
Mutagen
X ray
(Campbell et al., 1991, Panshin, 1935)
Progenitor genotype
Caused by aberration
In(1)sd2
Cytology

breakpoints unknown. No visible X-chromosome rearrangement in vicinity of 13F (Campbell, Duttaroy, Katzen and Chovnick, 1991).

Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sd2; ctL32 and sd2; ct2s double heterozygotes display a visible cut wing phenotype.

      (Morcillo et al., 1996)

      Homozygotes exhibit gaps in the bristle row along most of the wing margin. Double mutant combinations with ct46l and ct53d have a more extreme phenotype than the sd2 homozygotes. sd2 enhances the wing margin phenotype of ctL32.

      (Jack and DeLotto, 1992)

      Weak nibbled wing margin phenotype and ectopic bristles are present on the wing veins.

      (Campbell et al., 1991)

      Extreme allele; wings are small and scalloped, like vestigial at high temperature.

      (Panshin, 1935)

      More extreme than sd. Wings small and scalloped. Like vg at high temperatures. Crossing over inhibited. RK2A?

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      ct2s, sd2 has wing phenotype

      (Morcillo et al., 1996)

      ctL32, sd[+]/sd2 has wing phenotype

      (Morcillo et al., 1996)

      ctL32, sd[+]/sd2 has wing margin phenotype

      (Morcillo et al., 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Panshin, 7th July 1933.

      Panshin

      (Panshin, 1935)
      Comments
      Comments

      sd2 mutants are more sensitive to ct wing margin enhancer deletions that gypsy insertions in ct.

      (Morcillo et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      sd2
      Name Synonyms
      Secondary FlyBase IDs
        References (5)