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General Information
Symbol
Dmel\sls1
Species
D. melanogaster
Name
FlyBase ID
FBal0015717
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

sls1 heterozygous adults have an apparently normal morphology and are able to fly.

The lethality caused by sevS11.T:Hsap\MYC in combination with Ras85DV12.sev is not suppressed by sls1.

Mutation changes the level of w expression in ph-plac+3 flies; eye colour is lighter.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
NOT Suppressor of
Statement
Reference

sls1 is a non-suppressor of lethal phenotype of Ras85DV12.sev, sevS11.Tag:MYC

Phenotype Manifest In
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

sls1/sls[+] is a suppressor | partially of adult mesothoracic segment | ectopic phenotype of E(z)Trm

sls1/sls[+] is a suppressor | partially of adult metathoracic segment phenotype of E(z)Trm

sls1/sls[+] is a suppressor | partially of adult prothoracic segment phenotype of E(z)Trm

sls1 is a suppressor of phenotype of Pc4

Additional Comments
Genetic Interactions
Statement
Reference

Heterozygosity for sls1 enhances the semi-lethality and the myofibril shredding defects (even leading to the loss of the sarcomere structure) resulting from the expression of cherJF02077 under the control of Scer\GAL4Mef2.PU.

Dominant suppressor of the extra-sex-combs phenotype of heterozygous Pc alleles. Also suppresses the dominant extra-sex-combs phenotype of Pcl alleles.

Suppresses the extra sex comb phenotype of Pc4, Ts(YLt;2Lt)L124. Causes between 50% and 100% suppression of the Pc4/+ extra sex combs phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (20)