hypomorphic allele - genetic evidence
Q263R | spz-PA; Q237R | spz-PB; Q190R | spz-PC; Q210R | spz-PD; Q164R | spz-PI; Q181R | spz-PJ; Q227R | spz-PK; Q207R | spz-PL
Amino acid replacement: Q207R.
Nucleotide substitution: A620G.
lethal - all die during embryonic stage | maternal effect | recessive
some die during embryonic stage | recessive | maternal effect | recessive
embryonic/first instar larval cuticle | dorsal | maternal effect
embryonic/first instar larval cuticle | lateral | maternal effect
embryonic/first instar larval cuticle | maternal effect | ventral
VA1d olfactory receptor neuron axon targeting is normal in mutant flies.
Embryonic lethal when heterozygous with the MBT chromosome.
Affected embryos show preferential loss of ventral structures and the expansion of lateral and dorsal structures.
Embryos derived from spz2/spz3 females are weakly dorsalised at 18oC. The mesoderm and ventral furrow are reduced in size, and mesoderm only develops in the posterior part of the embryo.
temperature-sensitive Temperature-sensitive period of spz3 extends from oogenesis through fertilization until about the time of pole-cell formation
spz3, srn88 has lethal | pupal stage phenotype
spz3/pll2, spz3/pll8 or spz3/pll1 does not result in neoplasms.