FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Su(Tpl)17
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General Information
Symbol
Dmel\Su(Tpl)17
Species
D. melanogaster
Name
FlyBase ID
FBal0017001
Feature type
allele
Associated gene
Dmel\Su(Tpl)
Associated Insertion(s)
Carried in Construct
Also Known As
Tpl17
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Lindsley and Zimm, 1992)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q789term.

(Eissenberg, 2003.4.16, Eissenberg et al., 2002)

Possible insertion of an unidentified mobile element.

(Dorer and Christensen, 1990)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:19,892,339..19,892,339 [-]
Nucleotide change:

C19892339T

Amino acid change:

Q789term | Su(Tpl)-PA; Q789term | Su(Tpl)-PB; Q789term | Su(Tpl)-PC

Reported amino acid change:

Q789term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Eissenberg, 2003.4.16, Eissenberg et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The hetero-allelic combination Su(Tpl)17/Su(Tpl)S-192 is embryonic lethal. Mutant cuticles display the following defects, with variable penetrance: abdominal segment 4 missing or fused to abdominal segment 3 or 5; abdominal segment 6 incomplete or fused to abdominal segment 5; incomplete head involution.

      (Eissenberg et al., 2002)

      Site-specific increase in recombination frequency and premeiotic recombination in males.

      (Dorer and Christensen, 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Su(Tpl)[+]/Su(Tpl)17 is an enhancer of visible | dominant phenotype of Bx1

      (Bejarano et al., 2008)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Su(Tpl)[+]/Su(Tpl)17 is an enhancer of wing margin phenotype of Bx1

      (Bejarano et al., 2008)

      Su(Tpl)[+]/Su(Tpl)17 is an enhancer of wing margin phenotype of Nnd-1

      (Eissenberg et al., 2002)

      Su(Tpl)[+]/Su(Tpl)17 is an enhancer of wing margin phenotype of ct53d

      (Eissenberg et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      This mutation was previously reported to be an allele of Tpl (FBrf0051978). However, the effect on Tpl has been found not to map to the Tpl locus itself at 83E, but instead maps to a separate locus called Su(Tpl) at 76B-76D.

      (Dorer et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Su(Tpl)17
      (Bejarano et al., 2008)
      Tpl17
      (Lindsley and Zimm, 1992, Dorer and Christensen, 1990, Homyk and Emerson, 1988)
      Tplrv4
      (Lindsley and Zimm, 1992)
      Name Synonyms
      Secondary FlyBase IDs
        References (10)