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General Information
Symbol
Dmel\wIR1
Species
D. melanogaster
Name
Inducer Reactive 1
FlyBase ID
FBal0018259
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of an I-element.

A full length I-element is inserted into the 5th intron at position -1448 (FBrf0041384). The transcriptional orientation of the I-element is opposite to that of the w locus.

Insertion into non-translated region of the w gene.

Antiparallel I-element insertion into intron 5.

I element insertion.

An I-element maps either at the site of mutation or within less than 0.02 map units.

5.4kb I-element insertion map site (kb): -1.45; Origin = insertion of wa copia; '-' values to left (telomere) end; '+' values to right (centromere) end.

Insertion components
I{}wIR1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies have red-brown eyes.

Eye colour: brownish at 20oC and a lighter colour at 25oC.

Eye colour: brownish at 20oC, lighter at 25oC. Eye colour: z1 wIR1 males mottled orange eyes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference

wIR1 has abnormal eye color | recessive phenotype, suppressible by Rga[+]/Rga03834

wIR1 has abnormal eye color | recessive phenotype, suppressible by Low1

Phenotype Manifest In
Enhanced by
Statement
Reference

wIR1 has phenotype, enhanceable by Mowgamma

wIR1 has phenotype, enhanceable by Wowγb

wIR1 has phenotype, enhanceable by Wowγe

wIR1 has phenotype, enhanceable by Wowems1

wIR1 has phenotype, enhanceable by Wowhd1

wIR1 has phenotype, enhanceable by Rm62D

wIR1 has phenotype, enhanceable by Rm62Dem

wIR1 has phenotype, enhanceable by Rm62E

wIR1 has phenotype, enhanceable by Rm62F

wIR1 has phenotype, enhanceable by Rm62H

wIR1 has phenotype, enhanceable by Rm62K

NOT Enhanced by
Statement
Reference

wIR1 has phenotype, non-enhanceable by Ufo1

wIR1 has phenotype, non-enhanceable by In(3)Msu1

wIR1 has phenotype, non-enhanceable by In(3)Msu2

wIR1 has phenotype, non-enhanceable by E(wa)1

wIR1 has phenotype, non-enhanceable by DoaHD

wIR1 has phenotype, non-enhanceable by Doa3

wIR1 has phenotype, non-enhanceable by Doa4

wIR1 has phenotype, non-enhanceable by Doa5

wIR1 has phenotype, non-enhanceable by Doa6

wIR1 has phenotype, non-enhanceable by Doa7

wIR1 has phenotype, non-enhanceable by Doa8

wIR1 has phenotype, non-enhanceable by Doa9

Suppressed by
Statement
Reference

wIR1 has pigment cell phenotype, suppressible by Rga[+]/Rga03834

wIR1 has pigment cell phenotype, suppressible by Low1

NOT suppressed by
Statement
Reference

wIR1 has phenotype, non-suppressible by Ufo1

wIR1 has phenotype, non-suppressible by In(3)Msu1

wIR1 has phenotype, non-suppressible by In(3)Msu2

wIR1 has phenotype, non-suppressible by DoaHD

wIR1 has phenotype, non-suppressible by Doa3

wIR1 has phenotype, non-suppressible by Doa4

wIR1 has phenotype, non-suppressible by Doa5

wIR1 has phenotype, non-suppressible by Doa6

wIR1 has phenotype, non-suppressible by Doa7

wIR1 has phenotype, non-suppressible by Doa8

wIR1 has phenotype, non-suppressible by Doa9

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Pelisson.

Comments
Comments

Somewhat unstable under IR dysgenic conditions.

Used to test PCR amplification between gene-specific primers and I-element primers.

The I-element insertion in wIR1 interferes with the normal processing of w gene transcripts.

External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
wIR1
Name Synonyms
Inducer Reactive 1
Secondary FlyBase IDs
    References (21)