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General Information
Symbol
Dmel\wsat
Species
D. melanogaster
Name
satsuma
FlyBase ID
FBal0018300
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

TTC2791025GGC

Reported nucleotide change:

TT5317GG

Amino acid change:

F590G | w-PA

Reported amino acid change:

F590G

Comment:

The reported Phe590 to Gly amino acid change (TTC to GGC) requires substitution at two positions in the codon.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: F590G. Mutation is at the C-terminal end of putative transmembrane spanning α-helix 5.

Point mutation in the structural portion of w.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes have brown-orange eyes with only 7% red pigment (compared to 100% pigment in wild type).

Drosopterin (red pigment) levels are 4% of wild-type levels, xanthommatin levels (brown pigments) are 79% of wild-type levels.

Eye colour: deep ruby.

Eye colour: deep ruby Malpighian tubule colour: nearly wild-type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

wsat has abnormal eye color | recessive phenotype, suppressible by Low1

Enhancer of
Statement
Reference

wsat/we(g) is an enhancer of abnormal eye color phenotype of g53d

wsat/we(g) is an enhancer of abnormal eye color phenotype of g2

NOT Enhancer of
Statement
Reference

wsat/we(g) is a non-enhancer of abnormal eye color phenotype of g50e

Phenotype Manifest In
Enhanced by
Statement
Reference

wsat has phenotype, enhanceable by Ufo1

wsat has phenotype, enhanceable by Wowγb

wsat has phenotype, enhanceable by Wowγe

wsat has phenotype, enhanceable by Wowems1

wsat has phenotype, enhanceable by Wowhd1

NOT Enhanced by
Statement
Reference

wsat has phenotype, non-enhanceable by In(3)Msu1

wsat has phenotype, non-enhanceable by In(3)Msu2

wsat has phenotype, non-enhanceable by E(wa)1

wsat has phenotype, non-enhanceable by Doa4

wsat has phenotype, non-enhanceable by Doa5

wsat has phenotype, non-enhanceable by Doa6

wsat has phenotype, non-enhanceable by Doa7

wsat has phenotype, non-enhanceable by Doa8

wsat has phenotype, non-enhanceable by Doa9

wsat has phenotype, non-enhanceable by DoaHD

wsat has phenotype, non-enhanceable by Doa3

Suppressed by
Statement
Reference

wsat has pigment cell phenotype, suppressible by Low1

wsat has phenotype, suppressible by Mowgamma

wsat has phenotype, suppressible by Pcf11γb

wsat has phenotype, suppressible by Pcf11γc

wsat has phenotype, suppressible by Pcf11γd

wsat has phenotype, suppressible by Pcf11EMS3

wsat has phenotype, suppressible by Pcf11EMS4

wsat has phenotype, suppressible by Pcf11EMS5

wsat has phenotype, suppressible by Pcf11hd1

NOT suppressed by
Statement
Reference

wsat has phenotype, non-suppressible by In(3)Msu1

wsat has phenotype, non-suppressible by In(3)Msu2

wsat has phenotype, non-suppressible by Doa9

wsat has phenotype, non-suppressible by DoaHD

wsat has phenotype, non-suppressible by Doa3

wsat has phenotype, non-suppressible by Doa4

wsat has phenotype, non-suppressible by Doa5

wsat has phenotype, non-suppressible by Doa6

wsat has phenotype, non-suppressible by Doa7

wsat has phenotype, non-suppressible by Doa8

wsat has phenotype, non-suppressible by su(Hw)2

Enhancer of
Statement
Reference

wsat/we(g) is an enhancer of pigment cell phenotype of g53d

wsat/we(g) is an enhancer of pigment cell phenotype of g2

NOT Enhancer of
Statement
Reference

wsat/we(g) is a non-enhancer of pigment cell phenotype of g50e

Additional Comments
Genetic Interactions
Statement
Reference

Flies with a wsat/we(g) mutant genotype enhance the eye colour defective phenotype of g2 homozygous mutants leading to a greater reduction of red pigment in the eye. In contrast, wsat/we(g), g50e mutants have similar levels of red pigment in the eye to single g50e mutants.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (2)
Stocks (2)
Notes on Origin
Discoverer

Bridges, 26th Dec. 1933.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
w331
w33l
wsat
Name Synonyms
satsuma
Secondary FlyBase IDs
  • FBal0018099
References (16)