FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Psc1445
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General Information
Symbol
Dmel\Psc1445
Species
D. melanogaster
Name
FlyBase ID
FBal0030045
Feature type
allele
Associated gene
Dmel\Psc
Associated Insertion(s)
Carried in Construct
Also Known As
Psc14-45
Key Links
Allele class

hypomorphic allele - genetic evidence

loss of function allele

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Martin and Adler, 1993, Adler et al., 1989)

loss of function allele

(Wu and Howe, 1995)
Mutagen
ethyl methanesulfonate
(Martin and Adler, 1993)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
DQ022538
AAZ20642
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutation changes the level of w expression in ph-plac+3 flies; eye colour is lighter.

      (Fauvarque et al., 1995)

      Eye colour: Males bearing Psc1445 show a subtle lightening of eye colour.

      (Wu and Howe, 1995)

      Homozygous embryos die as late embryos with head defects.

      (Martin and Adler, 1993)

      Hypomorphic with respect to homeotic function.

      (Simon et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Psc1445, Su(z)21 has visible | dominant phenotype

      (Wu and Howe, 1995)
      Phenotype Manifest In
      Other
      Statement
      Reference

      Psc1445, Su(z)21 has microchaeta phenotype

      (Wu and Howe, 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Suppresses z1 eye color in a background of Su(z)24 or Su(z)31, and in a Su(z)2+ or Su(z)3+ background. Transheterozygotes with Su(z)21 show a subtle reduction in microchaetae.

      (Wu and Howe, 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Weak Psc allele.

      (Adler et al., 1989)

      abd-A expression is seen in parasegments 2 to 6 at 9 hours, by 12 hours expression has become much weaker. By 9 hours Abd-B is seen throughout the A-P axis.

      (Simon et al., 1992)

      Member of the "hapless" class of Psc alleles, i.e. lethal in trans to other "hapless" alleles and deficiencies of the region.

      (Wu and Howe, 1995)
      External Crossreferences and Linkouts ( 2 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Psc14-45
      (Simon et al., 1993, Simon et al., 1992)
      Psc1445
      l(2)49Ea3
      vr14-45
      vr1445
      Name Synonyms
      Secondary FlyBase IDs
        References (7)