FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\psq0115
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General Information
Symbol
Dmel\psq0115
Species
D. melanogaster
Name
FlyBase ID
FBal0032490
Feature type
allele
Associated gene
Dmel\psq
Associated Insertion(s)
P{PZ}psq0115
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Siegel et al., 1993)
Mutagen
P-element activity
(Horowitz and Berg, 1995, Siegel et al., 1993)
Progenitor genotype
Associated Insertion(s)
P{PZ}psq0115
Cytology
Description

P{PZ} insertion into the largest intron.

(Horowitz and Berg, 1996)

P{PZ} insertion within psq coding region.

(Horowitz and Berg, 1995)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
S77927
AAB33987
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos derived from psq0115/psqrum mutant females display terminal defects.

      (Grillo et al., 2011)

      Heterozygosity for psq0115 enhances the eye mottling phenotype seen in In(1)wm4h.

      (Schwendemann and Lehmann, 2002)

      Decreased viability, strong dorsalisation of eggshell and embryo and early oogenesis defects. Heat induced expression of P{hs-psq} result in the production of eggs, over 60% eggs laid have two dorsal appendages but none of the eggs hatch.

      (Horowitz and Berg, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      psq[+]/psq0115 is an enhancer of visible | dominant phenotype of Pc4

      (Huang et al., 2002)

      psq[+]/psq0115 is an enhancer of visible | dominant phenotype of Pc3

      (Schwendemann and Lehmann, 2002)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      psq[+]/psq0115 is an enhancer of leg phenotype of Pc4

      (Huang et al., 2002)

      psq[+]/psq0115 is an enhancer of sex comb | ectopic phenotype of Pc4

      (Huang et al., 2002)

      psq[+]/psq0115 is an enhancer of mesothoracic leg phenotype of Pc3

      (Schwendemann and Lehmann, 2002)

      psq[+]/psq0115 is an enhancer of metathoracic leg phenotype of Pc3

      (Schwendemann and Lehmann, 2002)

      psq[+]/psq0115 is an enhancer of sex comb | ectopic phenotype of Pc3

      (Schwendemann and Lehmann, 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The ectopic sex comb phenotype seen on the second and third legs of Pc4/+ males is dominantly enhanced by psq0115.

      (Huang et al., 2002)

      The penetrance of formation of ectopic sex combs on the mesothoracic and metathoracic legs of Pc3 heterozygous flies is significantly enhanced by heterozygosity for psq0115.

      (Schwendemann and Lehmann, 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Comments
      Comments

      Aberrant fusion protein created.

      (Horowitz and Berg, 1996)
      External Crossreferences and Linkouts ( 2 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      0115
      (Huang et al., 2002)
      psq0115
      (Bartoletti et al., 2012, Grillo et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)