FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\psq02403
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General Information
Symbol
Dmel\psq02403
Species
D. melanogaster
Name
FlyBase ID
FBal0032493
Feature type
allele
Associated gene
Dmel\psq
Associated Insertion(s)
P{PZ}psq02403
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Siegel et al., 1993)
Mutagen
P-element activity
(Horowitz and Berg, 1995, Siegel et al., 1993)
Progenitor genotype
Associated Insertion(s)
P{PZ}psq02403
Cytology
Description

P{PZ} insertion into the largest intron.

(Horowitz and Berg, 1996)

P{PZ} insertion within psq coding region.

(Horowitz and Berg, 1995)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Moderate dorsalisation of eggshell and embryo. P{hs-psq} can rescue the female sterile defect of psq02403; in the absence of heat shock 90% eggs have two dorsal appendages, with heat shock female fertility is restored.

      (Horowitz and Berg, 1996)

      Females lay few collapsed eggs with fused dorsal appendages. Nurse cell DNA remains condensed.

      (Siegel et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      psq[+]/psq02403 is an enhancer of visible | dominant phenotype of Pc4

      (Huang et al., 2002)

      psq[+]/psq02403 is an enhancer of visible | dominant phenotype of Psc1

      (Huang et al., 2002)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      psq[+]/psq02403 is an enhancer of leg phenotype of Pc4

      (Huang et al., 2002)

      psq[+]/psq02403 is an enhancer of sex comb | ectopic phenotype of Pc4

      (Huang et al., 2002)

      psq[+]/psq02403 is an enhancer of leg phenotype of Psc1

      (Huang et al., 2002)

      psq[+]/psq02403 is an enhancer of sex comb | ectopic phenotype of Psc1

      (Huang et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The ectopic sex comb phenotype seen on the second and third legs of Pc4/+ males is dominantly enhanced by psq02403.

      Psc1 psq02403 double heterozygous males show a remarkable increase in the number of ectopic sex comb teeth compared to Psc1 single heterozygotes.

      (Huang et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Comments
      Comments

      Aberrant fusion protein created.

      (Horowitz and Berg, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      2403
      (Huang et al., 2002)
      fs(2)02403
      (Spradling et al., 1999)
      pipsqueak2403
      (Schnorr et al., 2001)
      psq02403
      psq2403
      (Hodgson et al., 2001)
      psqPZ2403
      (Horowitz and Berg, 1995)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)