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General Information
Symbol
Dmel\roDOM
Species
D. melanogaster
Name
FlyBase ID
FBal0032584
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Rearrangement breaks 5' to the ro gene though the coding region of ro appears to be intact.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ommatidial clusters in roDOM/+ eye discs and adult eyes exhibit severe over-rotation.

Stop-furrow phenotype. Eye size reduced and kidney shaped due to premature arrest of morphogenetic furrow progression. Ommatidial number reduced to fewer than 100.

Arrests movement of the morphogenetic furrow in the eye resulting in a reduced adult eye that specifically lacks the anterior portion of the retina. Eye discs of third instar larvae display a 'furrow-stop' phenotype.

Reduced eye. The progression of the morphogenetic furrow in the developing eye disc arrests. The eye disc appears normal at the time of arrest. dpp expression is abolished (as assayed with a dpp-lacZ fusion gene).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

roDOM has visible phenotype, enhanceable by Dl1333/Dl[+]

roDOM has visible phenotype, enhanceable by E(roDOM)10651483/E(ro[DOM])1065[+]

roDOM has visible phenotype, enhanceable by E(roDOM)17771777/E(ro[DOM])1777[+]

roDOM has visible phenotype, enhanceable by E(ro[DOM])1777[+]/E(roDOM)17772586

roDOM has visible phenotype, enhanceable by E(ro[DOM])1801[+]/E(roDOM)18011801

roDOM has visible phenotype, enhanceable by E(ro[DOM])1801[+]/E(roDOM)18012796

roDOM has visible phenotype, enhanceable by E(ro[DOM])2051[+]/E(roDOM)20512051

roDOM has visible phenotype, enhanceable by E(ro[DOM])2051[+]/E(roDOM)20512376

roDOM has visible phenotype, enhanceable by E(ro[DOM])2409[+]/E(roDOM)24092409

roDOM has visible phenotype, enhanceable by E(roDOM)32223222/E(ro[DOM])3222[+]

roDOM has visible phenotype, enhanceable by E(ro[DOM])50[+]/E(roDOM)501766

roDOM has visible phenotype, enhanceable by Dl1650/Dl[+]

roDOM has visible phenotype, enhanceable by E(roDOM)5050/E(ro[DOM])50[+]

roDOM has visible phenotype, enhanceable by ato1/ato[+]

roDOM has visible phenotype, enhanceable by gl[+]/gl179

roDOM has visible phenotype, enhanceable by ptcS2/ptc[+]

roDOM has visible phenotype, enhanceable by Dl2821/Dl[+]

roDOM has visible phenotype, enhanceable by Dl51/Dl[+]

roDOM has visible phenotype, enhanceable by E(ro[DOM])1065[+]/E(roDOM)10651065

Suppressed by
Statement
Reference

roDOM has visible | dominant phenotype, suppressible | partially by amos[+]/amosRoi-Rev

roDOM has visible | dominant phenotype, suppressible by amosRoi-1/amos[+]

roDOM has visible phenotype, suppressible by H[+]/H1171

roDOM has visible phenotype, suppressible by Su(ro[DOM])1480[+]/Su(roDOM)14802104

roDOM has visible phenotype, suppressible by Su(ro[DOM])1993[+]/Su(roDOM)19931993

roDOM has visible phenotype, suppressible by Su(ro[DOM])1993[+]/Su(roDOM)19932088

roDOM has visible phenotype, suppressible by Su(ro[DOM])2014[+]/Su(roDOM)20142014

roDOM has visible phenotype, suppressible by Su(ro[DOM])3023[+]/Su(roDOM)30233023

roDOM has visible phenotype, suppressible by Su(roDOM)3023877/Su(ro[DOM])3023[+]

roDOM has visible phenotype, suppressible by Su(roDOM)345345/Su(ro[DOM])345[+]

roDOM has visible phenotype, suppressible by Su(roDOM)345617/Su(ro[DOM])345[+]

roDOM has visible phenotype, suppressible by Su(ro[DOM])519[+]/Su(roDOM)519519

roDOM has visible phenotype, suppressible by Su(ro[DOM])923[+]/Su(roDOM)9231275

roDOM has visible phenotype, suppressible by H1997/H[+]

roDOM has visible phenotype, suppressible by Su(ro[DOM])923[+]/Su(roDOM)923923

roDOM has visible phenotype, suppressible by gro1052/gro[+]

roDOM has visible phenotype, suppressible by gro131/gro[+]

roDOM has visible phenotype, suppressible by gro[+]/gro2053

roDOM has visible phenotype, suppressible by gro347/gro[+]

roDOM has visible phenotype, suppressible by gro781/gro[+]

roDOM has visible phenotype, suppressible by gro942/gro[+]

roDOM has visible phenotype, suppressible by hh[+]/hh1582

roDOM has visible phenotype, suppressible by hh[+]/hh8

roDOM has visible phenotype, suppressible by H299/H[+]

roDOM has visible phenotype, suppressible by osa1946/osa[+]

roDOM has visible phenotype, suppressible by osa[+]/osa2052

roDOM has visible phenotype, suppressible by osa2438/osa[+]

roDOM has visible phenotype, suppressible by osa2791/osa[+]

roDOM has visible phenotype, suppressible by osa[+]/osa308

roDOM has visible phenotype, suppressible by osa[+]/osa616

roDOM has visible phenotype, suppressible by ptcEP941/Scer\GAL4h-H10

roDOM has visible phenotype, suppressible by hh[+]/hh737

roDOM has visible phenotype, suppressible by H3194/H[+]

roDOM has visible phenotype, suppressible by Su(ro[DOM])1480[+]/Su(roDOM)14801480

roDOM has visible phenotype, suppressible by amosRoi-1/amos[+]

Phenotype Manifest In
Enhanced by
Statement
Reference

roDOM has eye phenotype, enhanceable by E(ro[DOM])1065[+]/E(roDOM)10651065

roDOM has eye phenotype, enhanceable by E(roDOM)10651483/E(ro[DOM])1065[+]

roDOM has eye phenotype, enhanceable by E(roDOM)17771777/E(ro[DOM])1777[+]

roDOM has eye phenotype, enhanceable by E(ro[DOM])1777[+]/E(roDOM)17772586

roDOM has eye phenotype, enhanceable by E(ro[DOM])1801[+]/E(roDOM)18011801

roDOM has eye phenotype, enhanceable by Dl1333/Dl[+]

roDOM has eye phenotype, enhanceable by E(ro[DOM])1801[+]/E(roDOM)18012796

roDOM has eye phenotype, enhanceable by E(ro[DOM])2051[+]/E(roDOM)20512051

roDOM has eye phenotype, enhanceable by E(ro[DOM])2051[+]/E(roDOM)20512376

roDOM has eye phenotype, enhanceable by E(ro[DOM])2409[+]/E(roDOM)24092409

roDOM has eye phenotype, enhanceable by E(roDOM)32223222/E(ro[DOM])3222[+]

roDOM has eye phenotype, enhanceable by E(ro[DOM])50[+]/E(roDOM)501766

roDOM has eye phenotype, enhanceable by E(roDOM)5050/E(ro[DOM])50[+]

roDOM has eye phenotype, enhanceable by ato1/ato[+]

roDOM has eye phenotype, enhanceable by gl[+]/gl179

roDOM has eye phenotype, enhanceable by Dl1650/Dl[+]

roDOM has eye phenotype, enhanceable by ptcS2/ptc[+]

roDOM has eye phenotype, enhanceable by Dl2821/Dl[+]

roDOM has eye phenotype, enhanceable by Dl51/Dl[+]

roDOM has phenotype, enhanceable by wgl-17

Suppressed by
Statement
Reference

roDOM has eye phenotype, suppressible | partially by amos[+]/amosRoi-Rev

roDOM has eye phenotype, suppressible by amosRoi-1/amos[+]

roDOM has eye phenotype, suppressible by Su(ro[DOM])1480[+]/Su(roDOM)14801480

roDOM has eye phenotype, suppressible by Su(ro[DOM])1480[+]/Su(roDOM)14802104

roDOM has eye phenotype, suppressible by Su(ro[DOM])1993[+]/Su(roDOM)19931993

roDOM has eye phenotype, suppressible by Su(ro[DOM])1993[+]/Su(roDOM)19932088

roDOM has eye phenotype, suppressible by Su(ro[DOM])2014[+]/Su(roDOM)20142014

roDOM has eye phenotype, suppressible by H[+]/H1171

roDOM has eye phenotype, suppressible by Su(ro[DOM])3023[+]/Su(roDOM)30233023

roDOM has eye phenotype, suppressible by Su(roDOM)3023877/Su(ro[DOM])3023[+]

roDOM has eye phenotype, suppressible by Su(roDOM)345345/Su(ro[DOM])345[+]

roDOM has eye phenotype, suppressible by Su(roDOM)345617/Su(ro[DOM])345[+]

roDOM has eye phenotype, suppressible by Su(ro[DOM])519[+]/Su(roDOM)519519

roDOM has eye phenotype, suppressible by Su(ro[DOM])923[+]/Su(roDOM)9231275

roDOM has eye phenotype, suppressible by Su(ro[DOM])923[+]/Su(roDOM)923923

roDOM has eye phenotype, suppressible by atoUAS.cJa/Scer\GAL4h-H10

roDOM has eye phenotype, suppressible by gro1052/gro[+]

roDOM has eye phenotype, suppressible by gro131/gro[+]

roDOM has eye phenotype, suppressible by H1997/H[+]

roDOM has eye phenotype, suppressible by gro[+]/gro2053

roDOM has eye phenotype, suppressible by gro347/gro[+]

roDOM has eye phenotype, suppressible by gro781/gro[+]

roDOM has eye phenotype, suppressible by gro942/gro[+]

roDOM has eye phenotype, suppressible by hh[+]/hh1582

roDOM has eye phenotype, suppressible by hh[+]/hh8

roDOM has eye phenotype, suppressible by osa1946/osa[+]

roDOM has eye phenotype, suppressible by osa[+]/osa2052

roDOM has eye phenotype, suppressible by osa2438/osa[+]

roDOM has eye phenotype, suppressible by osa2791/osa[+]

roDOM has eye phenotype, suppressible by H299/H[+]

roDOM has eye phenotype, suppressible by osa[+]/osa308

roDOM has eye phenotype, suppressible by osa[+]/osa616

roDOM has eye phenotype, suppressible by ptcEP941/Scer\GAL4h-H10

roDOM has eye phenotype, suppressible by hh[+]/hh737

roDOM has eye phenotype, suppressible by H3194/H[+]

roDOM has eye phenotype, suppressible by osa308

Additional Comments
Genetic Interactions
Statement
Reference

amosRoi-Rev/+ has some ability to suppress the furrow-stop eye phenotype of roDOM.

osa308 mutation suppresses the roDOM phenotype, not by allowing further progression of the furrow but by reinitiation of photoreceptor differentiation at the dorsal and ventral edges of the eye disc. Reduction of wg function reduces the eye size and the extent of photoreceptor differentiation along the disc margins.

Reduced eye phenotype is suppressed by amosRoi-1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

EMS-induced revertants of roDOM fail to complement loss of function alleles of ro.

Associated with a T(2;3) translocation that is not further described.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (11)