FlyBase Allele Report: Dmel\Adcy1[rut-178]

General Information

Symbol

Dmel\Adcy1^rut-178

Species

D. melanogaster

Name

FlyBase ID

FBal0032624

Feature type

allele

Associated gene

Dmel\Adcy1

Associated Insertion(s)

P{lArB}Adcy1^rut-178

Carried in Construct

Also Known As

P{lArB}rut¹⁷⁸

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

P-element activity

(Levin et al., 1992)

Delta2-3 transposase

(Han et al., 1996)

Progenitor genotype

P{lArB}A4.1M2

(Han et al., 1996)

Associated Insertion(s)

P{lArB}Adcy1^rut-178

Cytology

Description

P{lArB} insertion within 200bp upstream of the presumed transcription start site.

(Han et al., 1996)

Allele components

Component

Use(s)

Inserted element

P{lArB}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal memory | recessive

(Sakai et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

Unlike wild-type males, rut¹⁷⁸ homozygous males that have undergone courtship conditioning (kept in the presence of a female for 7 hours) do not spend significantly less time engaged in courtship behaviour when placed with a female 5 days after conditioning than non-conditioned males of the same genotype.

(Sakai et al., 2004)

Larval molting profile of rut²⁰⁸⁰/rut²⁰⁸⁰ and rut²⁰⁸⁰/rut¹⁷⁸ larvae appears normal.

(Venkatesh et al., 2001)

In an odour avoidance paradigm exhibits significantly reduced learning.

(Levin et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement