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General Information
Symbol
Dmel\Chc3
Species
D. melanogaster
Name
FlyBase ID
FBal0033513
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C15832408T

Amino acid change:

R366term | Chc-PA; R366term | Chc-PB; R366term | Chc-PC; R366term | Chc-PD; R366term | Chc-PE; R366term | Chc-PF; R366term | Chc-PG

Reported amino acid change:

R366term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

A nonsense mutation within the third coding exon.

Amino acid replacement: R366term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous mutant imaginal discs show neoplastic phenotypes.

Egg chambers containing Chc3 mutant germline clones show morphological defects.

No defects are seen in axon pruning during metamorphosis, or defects seen in the mushroom body.

Germline clonal analysis demonstrates an autonomous cell-lethal mutation in the female germline. Most embryos succeed in hatching, unhatched embryos show no regular cuticle defect.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Not rescued by

Chc3 is not rescued by ChcCHC2

Chc3 is not rescued by ChcCHC9

Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
  • FBal0039457
References (7)