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General Information
Symbol
Dmel\Ras85DSutor-341
Species
D. melanogaster
Name
FlyBase ID
FBal0033980
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

A9511745T

Amino acid change:

R131term | Ras85D-PA

Reported amino acid change:

R131term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The premature stop codon is predicted to result in a truncated protein that lacks the CAAX box.

Amino acid replacement: R131term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ras85DSutor-341/Ras85D05703 transheterozygotes have low viability. Females transheterozygotes with Ras85D05703 lay eggs with a severely disrupted eggshell (patch of chorion instead of dorsal appendages), 40% of eggs hatch and develop to normal larvae. Transheterozygotes with Ras85D05703 exhibit slightly disrupted ommatidial array (small number of fused and misplaced ommatidia).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

Ras85DSutor-341/Ras85D[+] is a suppressor of visible phenotype of EgfrE1

Phenotype Manifest In
Suppressor of
Statement
Reference

Ras85DSutor-341 is a suppressor of phenotype of tor11D

Ras85DSutor-341/Ras85D[+] is a suppressor of eye phenotype of EgfrE1

Additional Comments
Genetic Interactions
Statement
Reference

Weak suppression of the EgfrE1 rough eye phenotype and strong suppression of tor11D, embryos have 4 to 6 denticle belts.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Maternal and zygotic activity.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Ras1su(tor)341
Ras85DSutor-341
Su(tor)3-2341
Name Synonyms
Secondary FlyBase IDs
    References (4)