FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tea1755
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General Information
Symbol
Dmel\tea1755
Species
D. melanogaster
Name
FlyBase ID
FBal0039557
Feature type
allele
Associated gene
Dmel\tea
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(O'Brien et al., 1994)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q1638term.

(Zhang et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:9,897,544..9,897,544 [+]
Nucleotide change:

C9897544T

Reported nucleotide change:

C?T

Amino acid change:

Q1638term | tea-PB; Q1636term | tea-PC; Q1636term | tea-PD; Q1638term | tea-PE

Reported amino acid change:

Q1636term

(Zhang et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      tea1755/Df(2R)BSC298 as well as tea1755/tea2-1 mutants are larval lethal and their cells display high frequency of end-to-end chromosomal fusions during mitosis.

      (Zhang et al., 2016)

      Heterozygotes with l(2)46Cc1527 are semi-lethal.

      (O'Brien et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Df(2R)BSC298/tea1755 is rescued by tea+t10

      (Zhang et al., 2016)

      tea1755/tea2-1 is rescued by tea+t10

      (Zhang et al., 2016)
      Comments

      The larval lethality and chromosome end fusions characteristic for tea1755/Df(2R)BSC298 or tea2-1/tea1755 transheterozygotes mutants are each rescued by combination with tea+t10.

      (Zhang et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(2)1755
      (Zhang et al., 2016)
      l(2)46Cc1755
      tea1755
      (Zhang et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)