Open Close
General Information
Symbol
Dmel\phoc
Species
D. melanogaster
Name
FlyBase ID
FBal0039758
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

7.5kb gypsy insertion within an 86bp intron in the 5' non-coding region of the transcript.

Insertion components
gypsy{}phoc
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes, hemizygotes and heteroallelic with phoc die as pharate adults. Pupae exhibit transformation of antenna into legs, partial transformation of meso- and metathoracic legs into prothoracic, pattern duplications (presence of a sixth tarsal segment) and deficiencies in the legs (partial claw formation), partial transformation of abdominal segments to a more posterior identity and transformation of parovaria into spermathecia.

pupal lethal

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference

phoc is a suppressor of phenotype of nosunspecified

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Duncan.

Comments
Comments

Homozygotes die before pharate adult stage and hemizygotes survive with a weak pho phenotype. This suggests lethality could be due to a second site lethal. Recombinants were isolated, one gave a homozygous viable pho phenotype, the pho allele is referred to as phocv, it is not known if this is a partial revertant of phoc or removal of the second site lethal.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
l(4)102EFc4
pho102EFc-4
phoc
Name Synonyms
Secondary FlyBase IDs
  • FBal0011504
References (4)