FlyBase Allele Report: Ecol\lacZ[loco-rC56]

General Information

Symbol

Ecol\lacZ^loco-rC56

Species

E. coli

Name

FlyBase ID

FBal0041872

Feature type

allele

Associated gene

Ecol\lacZ

Associated Insertion(s)

P{lacZ.ry⁺}loco^rC56

Carried in Construct

Also Known As

rC56, P{lacZ-un1}loco^rC56, loco-lacZ

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Kretzschmar et al., 1997, Wemmer and Klämbt, 1995, Menne and Klambt, 1994)

Progenitor genotype

Associated Insertion(s)

P{lacZ.ry⁺}loco^rC56

Cytology

Description

The P{lacZ-un1} insertion is just upstream of the c1 transcript 5' UTR.

(Granderath et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{lacZ.ry⁺}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:22,626,614..22,626,967 [-]

(Ding et al., 2011, Kaplow et al., 2008, Thomas and van Meyel, 2007, Pielage et al., 2004, Shandala et al., 2003, Yuasa et al., 2003, Granderath et al., 2000, Granderath et al., 1999, Bernardoni et al., 1998, Klambt, 1998.8.10, Kretzschmar et al., 1997, Wemmer and Klämbt, 1995, Menne and Klambt, 1994)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

CNS glial cell | subset

(Menne and Klambt, 1994)

lateral ectoderm | dorsal

(Granderath et al., 1999)

embryonic stage 12

embryonic longitudinal glial cell

(Klaes et al., 1994)

glial cell of larval VUM neuron

(Klaes et al., 1994)

embryonic stage 12 -- 17

glial cell

(Granderath et al., 1999)

embryonic stage 13 -- 17

segmental nerve root glial cell

(Klaes et al., 1994)

exit glial cell

(Klaes et al., 1994)

larval B-subperineurial glial cell

(Klaes et al., 1994)

larval A-subperineurial glial cell

(Klaes et al., 1994)

medial intersegmental nerve root glial cell

(Klaes et al., 1994)

embryonic stage 16

larval lateral VNC glial cell

(Granderath et al., 2000)

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

larval glial cell

(Kaplow et al., 2008)

larval brain | restricted

(Kaplow et al., 2008)

eye disc

(Kaplow et al., 2008)

Additional Information

Statement

Reference

loco reporter expression is observed in most glial cells of the larval brain including surface, cortex, and neuropile glia. St

(Kaplow et al., 2008)

Enhancer trap expression is detected at embryonic stage 12 in cells which appear to be progeny of the lateral glioblast. Those cells migrate medially and divide. By the end of embryogenesis, enhancer trap expression is observed in most glial cells except the midline glia. Expression is also seen in the dorsal leading edge cells of the lateral ectoderm.

(Granderath et al., 1999)

Marker for

larval lateral VNC glial cell

(Granderath et al., 2000)

Reflects expression of

loco

(Kaplow et al., 2008, Granderath et al., 2000, Granderath et al., 1999)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

10009

P{lacZ.ry⁺}loco^rC56

Notes on Origin

Discoverer

Comments

"FBti0000730 == FBti0009198 == FBti0002154 == P{lacZ-un1}loco^rC56" was stated as revision.

(Granderath et al., 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ecol\lacZ^loco-rC56

Ecol\lacZ^rC56

lacZ^rC56

Name Synonyms

Secondary FlyBase IDs

References (14)

Report Sections

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