FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\eIF4Ak14518
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General Information
Symbol
Dmel\eIF4Ak14518
Species
D. melanogaster
Name
FlyBase ID
FBal0042539
Feature type
allele
Associated gene
Dmel\eIF4A
Associated Insertion(s)
P{lacW}eIF4Ak14518
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{lacW}eIF4Ak14518
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larval growth arrest, in L1. 60% survive until 6 days after hatching. 10% survive until 8 days after hatching. DNA replication ceases. Mutant phenotype is cell autonomous.

      (Galloni and Edgar, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      eIF-4a[+]/eIF4Ak14518 is a suppressor of visible | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      eIF-4a[+]/eIF4Ak14518 is a suppressor of eye | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      eIF4A02439

      (BDGP Project Members, 1994-1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      I. Kiss.

      Comments
      Comments

      Complements: lid10424. Complements: Kr-h110642.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Eif4ak14518
      eIF-4ak14518
      eIF4Ak14518
      l(2)k14518
      (Galloni and Edgar, 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)