FlyBase Allele Report: Dmel\S[k09530]

General Information

Symbol

Dmel\S^k09530

Species

D. melanogaster

Name

FlyBase ID

FBal0042734

Feature type

allele

Associated gene

Dmel\S

Associated Insertion(s)

P{lacW}S^k09530

Carried in Construct

Also Known As

k09530

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Kania et al., 1995)

Progenitor genotype

Associated Insertion(s)

P{lacW}S^k09530

Cytology

Description

Insertion of a P{lacW} element.

(Kania et al., 1995)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates multiple endocrine neoplasia type 2B

modeled by Ret^MEN2B.GMR

(Read et al., 2005)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Dworkin and Gibson, 2006, Spradling et al., 1999)

lethal - all die during embryonic stage | recessive

(Kania et al., 1995)

some die during embryonic stage | recessive

(Kania et al., 1995)

visible | dominant

(Dworkin and Gibson, 2006)

Phenotype Manifest In

chordotonal organ | lateral

(Kania et al., 1995)

fascicle

(Kania et al., 1995)

presumptive embryonic/larval peripheral nervous system

(Kania et al., 1995)

wing

(Dworkin and Gibson, 2006)

Detailed Description

Statement

Reference

Heterozygotes show a direct effect on the shape of the wing.

(Dworkin and Gibson, 2006)

Homozygous embryos exhibit defective organisation of the dorsal cluster, lateral chordotonal (Lch) neuron migration defects and occasional fasciculation defects.

(Kania et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

S^k09530 is a non-enhancer of visible phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Suppressor of

Statement

Reference

S^k09530/S[+] is a suppressor of visible phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

S^k09530 is a suppressor of visible phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

S^k09530/S[+] is a suppressor of visible | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

NOT Suppressor of

Statement

Reference

S^k09530 is a non-suppressor of visible phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

S^k09530/S[+] is an enhancer of eye phenotype of Dref^UAS.cSa

(Ida et al., 2009)

NOT Enhancer of

Statement

Reference

S^k09530 is a non-enhancer of eye phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Suppressor of

Statement

Reference

S^k09530/S[+] is a suppressor of wing vein | ectopic phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

S^k09530 is a suppressor of eye phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

S^k09530/S[+] is a suppressor of wing vein | ectopic | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

S^k09530/S[+] is a suppressor of wing | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

NOT Suppressor of

Statement

Reference

S^k09530 is a non-suppressor of eye phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

S⁰⁷⁰⁵⁶

(BDGP Project Members, 1994-1999)

S⁰⁵⁶⁷¹

(BDGP Project Members, 1994-1999)

S^k09541

(BDGP Project Members, 1994-1999)

S^k09534

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10418

y¹ w^67c23; P{lacW}S^k09530/CyO

Kyoto

111091

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{lacW}S^k09530 P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

Comments

P{lacW}S^k09530 and P{lacW}S^k09531 insertions might be members of the same cluster and not genuine alleles.

(Kania et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

95/30

(Kania et al., 1995)

S^k09530

(Ida et al., 2009, Oishi et al., 2006)

k09530

(Dworkin et al., 2011, Dworkin and Gibson, 2006)

l(2)k09530

(Spradling et al., 1999)

star^k09530

(Zhao et al., 2018, Dworkin and Gibson., 2006)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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