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General Information
Symbol
Dmel\RetMEN2A.GMR
Species
D. melanogaster
Name
FlyBase ID
FBal0189983
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GMR-dRetMEN2A
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

T21184913C

Reported nucleotide change:

T?C

Amino acid change:

C695R | Ret-PB; C695R | Ret-PA; C695R | Ret-PC

Reported amino acid change:

C695R

Comment:

Analogous mutation in human RET implicated in multiple endocrine neoplasia, type IIA; mutation carried on in vitro construct.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: C695R. Nucleotide substitution: C?T.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
is exacerbated by Mi-2S005504
is ameliorated by kisk10237
is ameliorated by Sk09538a
is exacerbated by Sin3Aex4
is exacerbated by msnj1E2
is ameliorated by SIIN
is exacerbated by Mi-2S147412
is ameliorated by spi1
is exacerbated by Sin3A08269
is ameliorated by Ras85D06677
is ameliorated by DlS049520
is exacerbated by hhrJ413
is ameliorated by Dl9P
is ameliorated by ebik16213
is ameliorated by spis3547
is ameliorated by drk10626
is exacerbated by hh2
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
This allele represents a human variant implicated in disease.
RET:p.Cys634Arg
Variants Synonym(s)
RET:p.Cys380Arg
Associated human disease model(s)
External database links
Comments concerning this variant
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of RetMEN2A.GMR results in a rough eye phenotype. Doubling the dose of RetMEN2A.GMR causes a very rough and small eye.

The retinas of pupae expressing two copies of RetMEN2A.GMR are primarily composed of ct- positive cone-like cells, and the few remaining cells display bristle morphology.

RetMEN2A.GMR flies have small (significant size decrease compared to wild type) rough eyes.

Flies carrying one copy of RetMEN2A.GMR have a rough eye phenotype. Flies carrying two copies of RetMEN2A.GMR have a severe eye phenotype, with the eye becoming an irregular mass.

Expression of RetMEN2A.GMR in the developing eye leads to overproliferation, alterations in cell fate differentiation, and ectopic cell death, giving rise to "rough" adult eyes consisting of fused, poorly patterned lenses and a reduction in the eyes' overall size.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

RetMEN2A.GMR has visible phenotype, enhanceable by Df(1)B25/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(1)sd72b/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(2L)H20/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(2L)TW137/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(2L)TW50/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(2L)cact-255rv64/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(1)C128/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(2R)CX1/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(2R)P34/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(2R)vg-C/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(3R)M-Kx1/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(3R)T-32/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(3R)e-N19/+

RetMEN2A.GMR has visible phenotype, enhanceable by Df(3R)e-R1/+

RetMEN2A.GMR has visible phenotype, enhanceable by RasGAP1B2

RetMEN2A.GMR has visible phenotype, enhanceable by Mi-2S005504/Mi-2[+]

RetMEN2A.GMR has visible phenotype, enhanceable by Df(1)KA14/+

RetMEN2A.GMR has visible phenotype, enhanceable by Mi-2S147412/Mi-2[+]

RetMEN2A.GMR has visible phenotype, enhanceable by Pp1-87B[+]/Pp1-87Bj6E7

RetMEN2A.GMR has visible phenotype, enhanceable by Sin3A[+]/Sin3A08269

RetMEN2A.GMR has visible phenotype, enhanceable by Sin3Aex4

RetMEN2A.GMR has visible phenotype, enhanceable by bonS048706/bon[+]

RetMEN2A.GMR has visible phenotype, enhanceable by crbj1B5/crb[+]

RetMEN2A.GMR has visible phenotype, enhanceable by hh2

RetMEN2A.GMR has visible phenotype, enhanceable by hh[+]/hhrJ413

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S000710[+]/l(3)S000710S000710

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S016805[+]/l(3)S016805S016805

RetMEN2A.GMR has visible phenotype, enhanceable by Df(1)RA2/+

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S023549S023549/l(3)S023549[+]

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S023549S090101/l(3)S023549[+]

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S023708[+]/l(3)S023708S023708

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S024329S024329/l(3)S024329[+]

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S024833[+]/l(3)S024833S024833

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S046604S046604/l(3)S046604[+]

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S066607[+]/l(3)S066607S066607

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S068808S068808/l(3)S068808[+]

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)S133117[+]/l(3)S133117S133117

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)j2D5j2D5/l(3)j2D5[+]

RetMEN2A.GMR has visible phenotype, enhanceable by Df(1)lz-90b24/+

RetMEN2A.GMR has visible phenotype, enhanceable by l(3)j4B9j4B9/l(3)j4B9[+]

RetMEN2A.GMR has visible phenotype, enhanceable by msn[+]/msnj1E2

RetMEN2A.GMR has visible phenotype, enhanceable by neur[+]/neurj6B12

RetMEN2A.GMR has visible phenotype, enhanceable by scrib[+]/scribj7B3

NOT Enhanced by
Statement
Reference

RetMEN2A.GMR has visible phenotype, non-enhanceable by Mi-2S047526/Mi-2[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by Pp1-87B1

RetMEN2A.GMR has visible phenotype, non-enhanceable by Sk09530

RetMEN2A.GMR has visible phenotype, non-enhanceable by crb11A22

RetMEN2A.GMR has visible phenotype, non-enhanceable by drkk02401

RetMEN2A.GMR has visible phenotype, non-enhanceable by drkk13809

RetMEN2A.GMR has visible phenotype, non-enhanceable by dsh3

RetMEN2A.GMR has visible phenotype, non-enhanceable by dsh6

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S000718[+]/l(3)S000718S000718

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S001405S001405/l(3)S001405[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S003704S003704/l(3)S003704[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S009515[+]/l(3)S009515S009515

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S012805S012805/l(3)S012805[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S019203S141715/l(3)S019203[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S026238S026238/l(3)S026238[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S026421S026421/l(3)S026421[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S056113[+]/l(3)S056113S056113

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S057101[+]/l(3)S057101S057101

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S081003S145911/l(3)S081003[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S090114[+]/l(3)S090114S090114

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S092708[+]/l(3)S092708S092708

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S135703S135703/l(3)S135703[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by l(3)S142909S142909/l(3)S142909[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by neur11

RetMEN2A.GMR has visible phenotype, non-enhanceable by px[+]/pxk08316

RetMEN2A.GMR has visible phenotype, non-enhanceable by stgS024503/stg[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by twsS049902/tws[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by Cskj1D8/Csk[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by CycAS054513/CycA[+]

RetMEN2A.GMR has visible phenotype, non-enhanceable by Df(2R)AA21/+

RetMEN2A.GMR has visible phenotype, non-enhanceable by Df(2R)Pu-D17/+

RetMEN2A.GMR has visible phenotype, non-enhanceable by Df(2R)ST1/+

RetMEN2A.GMR has visible phenotype, non-enhanceable by Df(3L)ZN47/+

Suppressed by
Statement
Reference

RetMEN2A.GMR has visible phenotype, suppressible by DJ-1alpha[+]/DJ-1αΔ72, dj-1βΔ93/dj-1βΔ93

RetMEN2A.GMR has visible phenotype, suppressible by Ras85D06677

RetMEN2A.GMR has visible phenotype, suppressible by SIIN

RetMEN2A.GMR has visible phenotype, suppressible by S[+]/Sk09538a

RetMEN2A.GMR has visible phenotype, suppressible by Src42Ak10108

RetMEN2A.GMR has visible phenotype, suppressible by Src64BPI

RetMEN2A.GMR has visible phenotype, suppressible by bsk1

RetMEN2A.GMR has visible phenotype, suppressible by bsk2

RetMEN2A.GMR has visible phenotype, suppressible by crb07207

RetMEN2A.GMR has visible phenotype, suppressible by drk10626

RetMEN2A.GMR has visible phenotype, suppressible by ebi[+]/ebik16213

RetMEN2A.GMR has visible phenotype, suppressible by kis[+]/kisk10237

RetMEN2A.GMR has visible phenotype, suppressible by ksrS-627

RetMEN2A.GMR has visible phenotype, suppressible by ksrj5E2

RetMEN2A.GMR has visible phenotype, suppressible by l(3)06803[+]/l(3)0680306803

RetMEN2A.GMR has visible phenotype, suppressible by l(3)06906[+]/l(3)0690606906

RetMEN2A.GMR has visible phenotype, suppressible by l(3)S023901[+]/l(3)S023901S023901

RetMEN2A.GMR has visible phenotype, suppressible by l(3)j5B6j5B6/l(3)j5B6[+]

RetMEN2A.GMR has visible phenotype, suppressible by neurA101

RetMEN2A.GMR has visible phenotype, suppressible by scrib1

RetMEN2A.GMR has visible phenotype, suppressible by scrib673

RetMEN2A.GMR has visible phenotype, suppressible by spi1

RetMEN2A.GMR has visible phenotype, suppressible by spis3547

RetMEN2A.GMR has visible phenotype, suppressible by Df(2L)TW161/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(2L)al/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(2L)net-PMF/+

RetMEN2A.GMR has visible phenotype, suppressible by +/Df(2R)59AD

RetMEN2A.GMR has visible phenotype, suppressible by Df(2R)X58-12/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(3L)Pc-2q/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(3R)Antp17/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(3R)Cha7/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(3R)DG2/+

RetMEN2A.GMR has visible phenotype, suppressible by +/Df(3R)Dl-BX12

RetMEN2A.GMR has visible phenotype, suppressible by Df(3R)Hu/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(3R)ME15/+

RetMEN2A.GMR has visible phenotype, suppressible by Df(3R)by10/+

RetMEN2A.GMR has visible phenotype, suppressible by Dl9P

RetMEN2A.GMR has visible phenotype, suppressible by DlS049520/Dl[+]

RetMEN2A.GMR has visible phenotype, suppressible by JraIA109

RetMEN2A.GMR has visible phenotype, suppressible by Pp1-87B2

NOT suppressed by
Statement
Reference

RetMEN2A.GMR has visible phenotype, non-suppressible by Cskj1D8/Csk[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by Df(3L)ZN47/+

RetMEN2A.GMR has visible phenotype, non-suppressible by Mi-2S047526/Mi-2[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by Pp1-87B1

RetMEN2A.GMR has visible phenotype, non-suppressible by Sk09530

RetMEN2A.GMR has visible phenotype, non-suppressible by crb11A22

RetMEN2A.GMR has visible phenotype, non-suppressible by CycAS054513/CycA[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by drkk02401

RetMEN2A.GMR has visible phenotype, non-suppressible by drkk13809

RetMEN2A.GMR has visible phenotype, non-suppressible by dsh3

RetMEN2A.GMR has visible phenotype, non-suppressible by dsh6

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S000718[+]/l(3)S000718S000718

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S001405S001405/l(3)S001405[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S003704S003704/l(3)S003704[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S009515[+]/l(3)S009515S009515

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S012805S012805/l(3)S012805[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S019203S141715/l(3)S019203[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by Df(2R)AA21/+

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S026238S026238/l(3)S026238[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S026421S026421/l(3)S026421[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S056113[+]/l(3)S056113S056113

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S057101[+]/l(3)S057101S057101

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S081003S145911/l(3)S081003[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S090114[+]/l(3)S090114S090114

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S092708[+]/l(3)S092708S092708

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S135703S135703/l(3)S135703[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by l(3)S142909S142909/l(3)S142909[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by neur11

RetMEN2A.GMR has visible phenotype, non-suppressible by Df(2R)Pu-D17/+

RetMEN2A.GMR has visible phenotype, non-suppressible by px[+]/pxk08316

RetMEN2A.GMR has visible phenotype, non-suppressible by stgS024503/stg[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by twsS049902/tws[+]

RetMEN2A.GMR has visible phenotype, non-suppressible by Df(2R)ST1/+

Phenotype Manifest In
Enhanced by
Statement
Reference

RetMEN2A.GMR has eye phenotype, enhanceable by Df(1)B25/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(1)sd72b/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(2L)H20/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(2L)TW137/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(2L)TW50/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(2L)cact-255rv64/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(2R)CX1/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(2R)P34/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(2R)vg-C/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(3R)M-Kx1/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(3R)T-32/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(1)C128/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(3R)e-N19/+

RetMEN2A.GMR has eye phenotype, enhanceable by Df(3R)e-R1/+

RetMEN2A.GMR has eye phenotype, enhanceable by RasGAP1B2

RetMEN2A.GMR has eye phenotype, enhanceable by In(2LR)DTD16LDTD42R/+

RetMEN2A.GMR has eye phenotype, enhanceable by Mi-2S005504/Mi-2[+]

RetMEN2A.GMR has eye phenotype, enhanceable by Mi-2S147412/Mi-2[+]

RetMEN2A.GMR has eye phenotype, enhanceable by Pp1-87B[+]/Pp1-87Bj6E7

RetMEN2A.GMR has eye phenotype, enhanceable by Sin3A[+]/Sin3A08269

RetMEN2A.GMR has eye phenotype, enhanceable by Sin3Aex4

RetMEN2A.GMR has eye phenotype, enhanceable by bonS048706/bon[+]

RetMEN2A.GMR has eye phenotype, enhanceable by Df(1)KA14/+

RetMEN2A.GMR has eye phenotype, enhanceable by crbj1B5/crb[+]

RetMEN2A.GMR has eye phenotype, enhanceable by hh2

RetMEN2A.GMR has eye phenotype, enhanceable by hh[+]/hhrJ413

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S000710[+]/l(3)S000710S000710

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S016805[+]/l(3)S016805S016805

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S023549S023549/l(3)S023549[+]

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S023549S090101/l(3)S023549[+]

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S023708[+]/l(3)S023708S023708

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S024329S024329/l(3)S024329[+]

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S024833[+]/l(3)S024833S024833

RetMEN2A.GMR has eye phenotype, enhanceable by Df(1)RA2/+

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S046604S046604/l(3)S046604[+]

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S066607[+]/l(3)S066607S066607

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S068808S068808/l(3)S068808[+]

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)S133117[+]/l(3)S133117S133117

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)j2D5j2D5/l(3)j2D5[+]

RetMEN2A.GMR has eye phenotype, enhanceable by l(3)j4B9j4B9/l(3)j4B9[+]

RetMEN2A.GMR has eye phenotype, enhanceable by msn[+]/msnj1E2

RetMEN2A.GMR has eye phenotype, enhanceable by neur[+]/neurj6B12

RetMEN2A.GMR has eye phenotype, enhanceable by scrib[+]/scribj7B3

RetMEN2A.GMR has eye phenotype, enhanceable by Df(1)lz-90b24/+

NOT Enhanced by
Statement
Reference

RetMEN2A.GMR has eye phenotype, non-enhanceable by Mi-2S047526/Mi-2[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by Pp1-87B1

RetMEN2A.GMR has eye phenotype, non-enhanceable by Sk09530

RetMEN2A.GMR has eye phenotype, non-enhanceable by crb11A22

RetMEN2A.GMR has eye phenotype, non-enhanceable by drkk02401

RetMEN2A.GMR has eye phenotype, non-enhanceable by drkk13809

RetMEN2A.GMR has eye phenotype, non-enhanceable by dsh3

RetMEN2A.GMR has eye phenotype, non-enhanceable by dsh6

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S000718[+]/l(3)S000718S000718

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S001405S001405/l(3)S001405[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S003704S003704/l(3)S003704[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S009515[+]/l(3)S009515S009515

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S012805S012805/l(3)S012805[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S019203S141715/l(3)S019203[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S026238S026238/l(3)S026238[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S026421S026421/l(3)S026421[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S056113[+]/l(3)S056113S056113

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S057101[+]/l(3)S057101S057101

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S081003S145911/l(3)S081003[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S090114[+]/l(3)S090114S090114

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S092708[+]/l(3)S092708S092708

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S135703S135703/l(3)S135703[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by l(3)S142909S142909/l(3)S142909[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by neur11

RetMEN2A.GMR has eye phenotype, non-enhanceable by px[+]/pxk08316

RetMEN2A.GMR has eye phenotype, non-enhanceable by stgS024503/stg[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by twsS049902/tws[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by Cskj1D8/Csk[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by CycAS054513/CycA[+]

RetMEN2A.GMR has eye phenotype, non-enhanceable by Df(2R)AA21/+

RetMEN2A.GMR has eye phenotype, non-enhanceable by Df(2R)Pu-D17/+

RetMEN2A.GMR has eye phenotype, non-enhanceable by Df(2R)ST1/+

RetMEN2A.GMR has eye phenotype, non-enhanceable by Df(3L)ZN47/+

Suppressed by
Statement
Reference

RetMEN2A.GMR has eye | adult stage phenotype, suppressible by DJ-1alpha[+]/DJ-1αΔ72, dj-1βΔ93/dj-1βΔ93

RetMEN2A.GMR has eye phenotype, suppressible by Ras85D06677

RetMEN2A.GMR has eye phenotype, suppressible by SIIN

RetMEN2A.GMR has eye phenotype, suppressible by S[+]/Sk09538a

RetMEN2A.GMR has eye phenotype, suppressible by Src42Ak10108

RetMEN2A.GMR has eye phenotype, suppressible by Src64BPI

RetMEN2A.GMR has eye phenotype, suppressible by bsk1

RetMEN2A.GMR has eye phenotype, suppressible by bsk2

RetMEN2A.GMR has eye phenotype, suppressible by crb07207

RetMEN2A.GMR has eye phenotype, suppressible by drk10626

RetMEN2A.GMR has eye phenotype, suppressible by ebi[+]/ebik16213

RetMEN2A.GMR has eye phenotype, suppressible by kis[+]/kisk10237

RetMEN2A.GMR has eye phenotype, suppressible by ksrS-627

RetMEN2A.GMR has eye phenotype, suppressible by ksrj5E2

RetMEN2A.GMR has eye phenotype, suppressible by l(3)06803[+]/l(3)0680306803

RetMEN2A.GMR has eye phenotype, suppressible by l(3)06906[+]/l(3)0690606906

RetMEN2A.GMR has eye phenotype, suppressible by l(3)S023901[+]/l(3)S023901S023901

RetMEN2A.GMR has eye phenotype, suppressible by l(3)j5B6j5B6/l(3)j5B6[+]

RetMEN2A.GMR has eye phenotype, suppressible by neurA101

RetMEN2A.GMR has eye phenotype, suppressible by scrib1

RetMEN2A.GMR has eye phenotype, suppressible by scrib673

RetMEN2A.GMR has eye phenotype, suppressible by spi1

RetMEN2A.GMR has eye phenotype, suppressible by spis3547

RetMEN2A.GMR has eye phenotype, suppressible by Df(2L)TW161/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(2L)al/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(2L)net-PMF/+

RetMEN2A.GMR has eye phenotype, suppressible by +/Df(2R)59AD

RetMEN2A.GMR has eye phenotype, suppressible by Df(2R)X58-12/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(3L)Pc-2q/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(3R)Antp17/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(3R)Cha7/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(3R)DG2/+

RetMEN2A.GMR has eye phenotype, suppressible by +/Df(3R)Dl-BX12

RetMEN2A.GMR has eye phenotype, suppressible by Df(3R)Hu/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(3R)ME15/+

RetMEN2A.GMR has eye phenotype, suppressible by Df(3R)by10/+

RetMEN2A.GMR has eye phenotype, suppressible by Dl9P

RetMEN2A.GMR has eye phenotype, suppressible by DlS049520/Dl[+]

RetMEN2A.GMR has eye phenotype, suppressible by JraIA109

RetMEN2A.GMR has eye phenotype, suppressible by Pp1-87B2

NOT suppressed by
Statement
Reference

RetMEN2A.GMR has eye phenotype, non-suppressible by Cskj1D8/Csk[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by Df(3L)ZN47/+

RetMEN2A.GMR has eye phenotype, non-suppressible by Mi-2S047526/Mi-2[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by Pp1-87B1

RetMEN2A.GMR has eye phenotype, non-suppressible by Sk09530

RetMEN2A.GMR has eye phenotype, non-suppressible by crb11A22

RetMEN2A.GMR has eye phenotype, non-suppressible by drkk02401

RetMEN2A.GMR has eye phenotype, non-suppressible by drkk13809

RetMEN2A.GMR has eye phenotype, non-suppressible by dsh3

RetMEN2A.GMR has eye phenotype, non-suppressible by dsh6

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S000718[+]/l(3)S000718S000718

RetMEN2A.GMR has eye phenotype, non-suppressible by CycAS054513/CycA[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S001405S001405/l(3)S001405[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S003704S003704/l(3)S003704[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S009515[+]/l(3)S009515S009515

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S012805S012805/l(3)S012805[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S019203S141715/l(3)S019203[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S026238S026238/l(3)S026238[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S026421S026421/l(3)S026421[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S056113[+]/l(3)S056113S056113

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S057101[+]/l(3)S057101S057101

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S081003S145911/l(3)S081003[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by Df(2R)AA21/+

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S090114[+]/l(3)S090114S090114

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S092708[+]/l(3)S092708S092708

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S135703S135703/l(3)S135703[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by l(3)S142909S142909/l(3)S142909[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by neur11

RetMEN2A.GMR has eye phenotype, non-suppressible by px[+]/pxk08316

RetMEN2A.GMR has eye phenotype, non-suppressible by stgS024503/stg[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by twsS049902/tws[+]

RetMEN2A.GMR has eye phenotype, non-suppressible by Df(2R)Pu-D17/+

RetMEN2A.GMR has eye phenotype, non-suppressible by Df(2R)ST1/+

Additional Comments
Genetic Interactions
Statement
Reference

Expression of FakScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PU partially suppresses the small eye size induced by expression of one copy of RetMEN2A.GMR.

Expression of FakΔN.Scer\UAS under the control of Scer\GAL4GMR.PU does not suppress the small eye size induced by expression of one copy of RetMEN2A.GMR.

Expression of FakY430F.Scer\UAS under the control of Scer\GAL4GMR.PU partially suppresses the small eye size induced by expression of one copy of RetMEN2A.GMR.

Expression of FakScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PU partially suppresses the eye size defect and ectopic cone cell phenotype induced by expression of two copies of RetMEN2A.GMR, resulting in the reappearance of normal ommatidial cores and surrounding interommatidial cells in pupal retinas.

DJ-1αΔ72/+ dj-1βΔ93/dj-1βΔ93 significantly suppresses the small rough eye phenotype in RetMEN2A.GMR flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
RetMEN2A.GMR
Name Synonyms
Secondary FlyBase IDs
    References (5)